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Therapeutic potential of targeting the oncogenic SHP2 phosphatase.
Zeng LF, Zhang RY, Yu ZH, Li S, Wu L, Gunawan AM, Lane BS, Mali RS, Li X, Chan RJ, Kapur R, Wells CD, Zhang ZY. Zeng LF, et al. Among authors: yu zh. J Med Chem. 2014 Aug 14;57(15):6594-609. doi: 10.1021/jm5006176. Epub 2014 Jul 28. J Med Chem. 2014. PMID: 25003231 Free PMC article.
Protein tyrosine phosphatases as potential therapeutic targets.
He RJ, Yu ZH, Zhang RY, Zhang ZY. He RJ, et al. Among authors: yu zh. Acta Pharmacol Sin. 2014 Oct;35(10):1227-46. doi: 10.1038/aps.2014.80. Epub 2014 Sep 15. Acta Pharmacol Sin. 2014. PMID: 25220640 Free PMC article. Review.
A potent and selective inhibitor for the UBLCP1 proteasome phosphatase.
He Y, Guo X, Yu ZH, Wu L, Gunawan AM, Zhang Y, Dixon JE, Zhang ZY. He Y, et al. Among authors: yu zh. Bioorg Med Chem. 2015 Jun 15;23(12):2798-809. doi: 10.1016/j.bmc.2015.03.066. Epub 2015 Mar 31. Bioorg Med Chem. 2015. PMID: 25907364 Free PMC article.
Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.
He R, Yu ZH, Zhang RY, Wu L, Gunawan AM, Lane BS, Shim JS, Zeng LF, He Y, Chen L, Wells CD, Liu JO, Zhang ZY. He R, et al. Among authors: yu zh. ACS Med Chem Lett. 2015 Jun 8;6(7):782-6. doi: 10.1021/acsmedchemlett.5b00118. eCollection 2015 Jul 9. ACS Med Chem Lett. 2015. PMID: 26191366 Free PMC article.
454 results