Cherezov V - Search Results

1

Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs.

Wang C, Wu H, Evron T, Vardy E, Han GW, Huang XP, Hufeisen SJ, Mangano TJ, Urban DJ, Katritch V, Cherezov V, Caron MG, Roth BL, Stevens RC. Wang C, et al. Among authors: cherezov v. Nat Commun. 2014 Jul 10;5:4355. doi: 10.1038/ncomms5355. Nat Commun. 2014. PMID: 25008467 Free PMC article.

2

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.

Rosenbaum DM, Cherezov V, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Yao XJ, Weis WI, Stevens RC, Kobilka BK. Rosenbaum DM, et al. Among authors: cherezov v. Science. 2007 Nov 23;318(5854):1266-73. doi: 10.1126/science.1150609. Epub 2007 Oct 25. Science. 2007. PMID: 17962519

3

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.

Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Kuhn P, Weis WI, Kobilka BK, Stevens RC. Cherezov V, et al. Science. 2007 Nov 23;318(5854):1258-65. doi: 10.1126/science.1150577. Epub 2007 Oct 25. Science. 2007. PMID: 17962520 Free PMC article.

4

In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin.

Cherezov V, Liu W, Derrick JP, Luan B, Aksimentiev A, Katritch V, Caffrey M. Cherezov V, et al. Proteins. 2008 Apr;71(1):24-34. doi: 10.1002/prot.21841. Proteins. 2008. PMID: 18076035

5

A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor.

Hanson MA, Cherezov V, Griffith MT, Roth CB, Jaakola VP, Chien EY, Velasquez J, Kuhn P, Stevens RC. Hanson MA, et al. Among authors: cherezov v. Structure. 2008 Jun;16(6):897-905. doi: 10.1016/j.str.2008.05.001. Structure. 2008. PMID: 18547522 Free PMC article.

6

The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist.

Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, Ijzerman AP, Stevens RC. Jaakola VP, et al. Among authors: cherezov v. Science. 2008 Nov 21;322(5905):1211-7. doi: 10.1126/science.1164772. Epub 2008 Oct 2. Science. 2008. PMID: 18832607 Free PMC article.

7

LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization.

Cherezov V, Liu J, Griffith M, Hanson MA, Stevens RC. Cherezov V, et al. Cryst Growth Des. 2008;8(12):4307-4315. doi: 10.1021/cg800778j. Cryst Growth Des. 2008. PMID: 19234616 Free PMC article.

8

Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes.

Katritch V, Reynolds KA, Cherezov V, Hanson MA, Roth CB, Yeager M, Abagyan R. Katritch V, et al. Among authors: cherezov v. J Mol Recognit. 2009 Jul-Aug;22(4):307-18. doi: 10.1002/jmr.949. J Mol Recognit. 2009. PMID: 19353579 Free PMC article.

9

Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam.

Cherezov V, Hanson MA, Griffith MT, Hilgart MC, Sanishvili R, Nagarajan V, Stepanov S, Fischetti RF, Kuhn P, Stevens RC. Cherezov V, et al. J R Soc Interface. 2009 Oct 6;6 Suppl 5(Suppl 5):S587-97. doi: 10.1098/rsif.2009.0142.focus. Epub 2009 Jun 17. J R Soc Interface. 2009. PMID: 19535414 Free PMC article. Review.

10

LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment.

Liu W, Hanson MA, Stevens RC, Cherezov V. Liu W, et al. Among authors: cherezov v. Biophys J. 2010 Apr 21;98(8):1539-48. doi: 10.1016/j.bpj.2009.12.4296. Biophys J. 2010. PMID: 20409473 Free PMC article.

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