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Page 1
Haploinsufficiency of the insulin-like growth factor-1 receptor enhances endothelial repair and favorably modifies angiogenic progenitor cell phenotype.
Yuldasheva NY, Rashid ST, Haywood NJ, Cordell P, Mughal R, Viswambharan H, Imrie H, Sukumar P, Cubbon RM, Aziz A, Gage M, Mbonye KA, Smith J, Galloway S, Skromna A, Scott DJ, Kearney MT, Wheatcroft SB. Yuldasheva NY, et al. Among authors: skromna a. Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):2051-8. doi: 10.1161/ATVBAHA.114.304121. Epub 2014 Jul 10. Arterioscler Thromb Vasc Biol. 2014. PMID: 25012136
Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice.
Imrie H, Viswambharan H, Sukumar P, Abbas A, Cubbon RM, Yuldasheva N, Gage M, Smith J, Galloway S, Skromna A, Rashid ST, Futers TS, Xuan S, Gatenby VK, Grant PJ, Channon KM, Beech DJ, Wheatcroft SB, Kearney MT. Imrie H, et al. Among authors: skromna a. Diabetes. 2012 Sep;61(9):2359-68. doi: 10.2337/db11-1494. Epub 2012 Jun 25. Diabetes. 2012. PMID: 22733797 Free PMC article.
Endothelium-specific insulin resistance leads to accelerated atherosclerosis in areas with disturbed flow patterns: a role for reactive oxygen species.
Gage MC, Yuldasheva NY, Viswambharan H, Sukumar P, Cubbon RM, Galloway S, Imrie H, Skromna A, Smith J, Jackson CL, Kearney MT, Wheatcroft SB. Gage MC, et al. Among authors: skromna a. Atherosclerosis. 2013 Sep;230(1):131-9. doi: 10.1016/j.atherosclerosis.2013.06.017. Epub 2013 Jun 29. Atherosclerosis. 2013. PMID: 23958265
Endothelial SHIP2 Suppresses Nox2 NADPH Oxidase-Dependent Vascular Oxidative Stress, Endothelial Dysfunction, and Systemic Insulin Resistance.
Watt NT, Gage MC, Patel PA, Viswambharan H, Sukumar P, Galloway S, Yuldasheva NY, Imrie H, Walker AMN, Griffin KJ, Makava N, Skromna A, Bridge K, Beech DJ, Schurmans S, Wheatcroft SB, Kearney MT, Cubbon RM. Watt NT, et al. Among authors: skromna a. Diabetes. 2017 Nov;66(11):2808-2821. doi: 10.2337/db17-0062. Epub 2017 Aug 22. Diabetes. 2017. PMID: 28830894 Free article.
Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction.
Sukumar P, Viswambharan H, Imrie H, Cubbon RM, Yuldasheva N, Gage M, Galloway S, Skromna A, Kandavelu P, Santos CX, Gatenby VK, Smith J, Beech DJ, Wheatcroft SB, Channon KM, Shah AM, Kearney MT. Sukumar P, et al. Among authors: skromna a. Diabetes. 2013 Jun;62(6):2130-4. doi: 10.2337/db12-1294. Epub 2013 Jan 24. Diabetes. 2013. PMID: 23349484 Free PMC article.
Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential.
Cubbon RM, Yuldasheva NY, Viswambharan H, Mercer BN, Baliga V, Stephen SL, Askham J, Sukumar P, Skromna A, Mughal RS, Walker AM, Bruns A, Bailey MA, Galloway S, Imrie H, Gage MC, Rakobowchuk M, Li J, Porter KE, Ponnambalam S, Wheatcroft SB, Beech DJ, Kearney MT. Cubbon RM, et al. Among authors: skromna a. Stem Cells. 2014 Oct;32(10):2714-23. doi: 10.1002/stem.1766. Stem Cells. 2014. PMID: 24916783 Free article.
Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signaling Loop.
Viswambharan H, Yuldasheva NY, Sengupta A, Imrie H, Gage MC, Haywood N, Walker AM, Skromna A, Makova N, Galloway S, Shah P, Sukumar P, Porter KE, Grant PJ, Shah AM, Santos CX, Li J, Beech DJ, Wheatcroft SB, Cubbon RM, Kearney MT. Viswambharan H, et al. Among authors: skromna a. Circ Res. 2017 Mar 3;120(5):784-798. doi: 10.1161/CIRCRESAHA.116.309678. Epub 2016 Dec 5. Circ Res. 2017. PMID: 27920123 Free article.
Effects of obesity on insulin: insulin-like growth factor 1 hybrid receptor expression and Akt phosphorylation in conduit and resistance arteries.
Mughal RS, Bridge K, Buza I, Slaaby R, Worm J, Klitgaard-Povlsen G, Hvid H, Schiødt M, Cubbon R, Yuldasheva N, Skromna A, Makava N, Skytte-Olsen G, Kearney MT. Mughal RS, et al. Among authors: skromna a. Diab Vasc Dis Res. 2019 Mar;16(2):160-170. doi: 10.1177/1479164118802550. Epub 2018 Oct 8. Diab Vasc Dis Res. 2019. PMID: 30295509 Free PMC article.
Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance-related vascular damage.
Maqbool A, Watt NT, Haywood N, Viswambharan H, Skromna A, Makava N, Visnagri A, Shawer HM, Bridge K, Muminov SK, Griffin K, Beech DJ, Wheatcroft SB, Porter KE, Simmons KJ, Sukumar P, Shah AM, Cubbon RM, Kearney MT, Yuldasheva NY. Maqbool A, et al. Among authors: skromna a. Am J Physiol Cell Physiol. 2020 Jul 1;319(1):C64-C74. doi: 10.1152/ajpcell.00389.2019. Epub 2020 May 13. Am J Physiol Cell Physiol. 2020. PMID: 32401607 Free PMC article.
Endothelial IGF-1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity.
Haywood NJ, Luk C, Bridge KI, Drozd M, Makava N, Skromna A, Maccannell A, Ozber CH, Warmke N, Wilkinson CG, Watt NT, Koch-Paszkowski J, Teh I, Boyle JH, Smart S, Schneider JE, Yuldasheva NY, Roberts LD, Beech DJ, Sukumar P, Wheatcroft SB, Cubbon RM, Kearney MT. Haywood NJ, et al. Among authors: skromna a. EMBO Rep. 2021 May 5;22(5):e50767. doi: 10.15252/embr.202050767. Epub 2021 May 2. EMBO Rep. 2021. PMID: 33934497 Free PMC article.
17 results