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Discovery of 1-butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1H)-pyridone (JNJ-40411813): a novel positive allosteric modulator of the metabotropic glutamate 2 receptor.
Cid JM, Tresadern G, Duvey G, Lütjens R, Finn T, Rocher JP, Poli S, Vega JA, de Lucas AI, Matesanz E, Linares ML, Andrés JI, Alcazar J, Alonso JM, Macdonald GJ, Oehlrich D, Lavreysen H, Ahnaou A, Drinkenburg W, Mackie C, Pype S, Gallacher D, Trabanco AA. Cid JM, et al. Among authors: finn t. J Med Chem. 2014 Aug 14;57(15):6495-512. doi: 10.1021/jm500496m. Epub 2014 Jul 28. J Med Chem. 2014. PMID: 25032784
New positive allosteric modulators of the metabotropic glutamate receptor 2 (mGluR2): identification and synthesis of N-propyl-8-chloro-6-substituted isoquinolones.
Trabanco AA, Duvey G, Cid JM, Macdonald GJ, Cluzeau P, Nhem V, Furnari R, Behaj N, Poulain G, Finn T, Lavreysen H, Poli S, Raux A, Thollon Y, Poirier N, D'Addona D, Andrés JI, Lutjens R, Le Poul E, Imogai H, Rocher JP. Trabanco AA, et al. Among authors: finn t. Bioorg Med Chem Lett. 2011 Feb 1;21(3):971-6. doi: 10.1016/j.bmcl.2010.12.048. Epub 2010 Dec 21. Bioorg Med Chem Lett. 2011. PMID: 21232953
Discovery of 1,5-disubstituted pyridones: a new class of positive allosteric modulators of the metabotropic glutamate 2 receptor.
Cid JM, Duvey G, Cluzeau P, Nhem V, Macary K, Raux A, Poirier N, Muller J, Boléa C, Finn T, Poli S, Epping-Jordan M, Chamelot E, Derouet F, Girard F, Macdonald GJ, Vega JA, de Lucas AI, Matesanz E, Lavreysen H, Linares ML, Oehlrich D, Oyarzábal J, Tresadern G, Trabanco AA, Andrés JI, Le Poul E, Imogai H, Lutjens R, Rocher JP. Cid JM, et al. Among authors: finn t. ACS Chem Neurosci. 2010 Dec 15;1(12):788-95. doi: 10.1021/cn1000638. Epub 2010 Aug 23. ACS Chem Neurosci. 2010. PMID: 22778815 Free PMC article.
ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization.
Kalinichev M, Rouillier M, Girard F, Royer-Urios I, Bournique B, Finn T, Charvin D, Campo B, Le Poul E, Mutel V, Poli S, Neale SA, Salt TE, Lütjens R. Kalinichev M, et al. Among authors: finn t. J Pharmacol Exp Ther. 2013 Mar;344(3):624-36. doi: 10.1124/jpet.112.200915. Epub 2012 Dec 20. J Pharmacol Exp Ther. 2013. PMID: 23257312
Case-fatality rate of invasive pneumococcal disease caused by various serotypes-an analysis of nationwide surveillance data from Israel, 2009-2018.
Wieder-Finesod A, Yahav D, Rubin C, Hashkor S, Southern J, Mircus G, Theilacker C, Dagan R, Regev-Yochay G; Israeli Adult Invasive Pneumococcal Disease (IAIPD) Group. Wieder-Finesod A, et al. Clin Microbiol Infect. 2025 Feb;31(2):226-232. doi: 10.1016/j.cmi.2024.11.018. Epub 2024 Nov 15. Clin Microbiol Infect. 2025. PMID: 39551343
Men with HIV have increased alveolar bone loss.
Skelton M, Callahan C, Levit M, Finn TR, Kister K, Matsumura S, Cantos A, Shah J, Wadhwa S, Yin MT. Skelton M, et al. Among authors: finn tr. BMC Oral Health. 2024 Oct 19;24(1):1248. doi: 10.1186/s12903-024-04989-x. BMC Oral Health. 2024. PMID: 39427141 Free PMC article.
A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex.
Liang XG, Hoang K, Meyerink BL, Kc P, Paraiso K, Wang L, Jones IR, Zhang Y, Katzman S, Finn TS, Tsyporin J, Qu F, Chen Z, Visel A, Kriegstein A, Shen Y, Pilaz LJ, Chen B. Liang XG, et al. Among authors: finn ts. Proc Natl Acad Sci U S A. 2024 May 14;121(20):e2321711121. doi: 10.1073/pnas.2321711121. Epub 2024 May 7. Proc Natl Acad Sci U S A. 2024. PMID: 38713624 Free PMC article.
196 results