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Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65.
Shinozaki S, Chang K, Sakai M, Shimizu N, Yamada M, Tanaka T, Nakazawa H, Ichinose F, Yamada Y, Ishigami A, Ito H, Ouchi Y, Starr ME, Saito H, Shimokado K, Stamler JS, Kaneki M. Shinozaki S, et al. Among authors: tanaka t. Sci Signal. 2014 Nov 11;7(351):ra106. doi: 10.1126/scisignal.2005375. Sci Signal. 2014. PMID: 25389371 Free PMC article.
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