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PAKC: A novel panel of HLA class I antigen presentation machinery knockout cells from the same genetic origin.
de Waard AA, Verkerk T, Jongsma MLM, Hoefakker K, Sethumadhavan S, Gerke C, Bliss S, Kong X, Janssen GMC, de Ru AH, Claas FHJ, Mulder A, Tampé R, van Veelen PA, Halenius A, Spaapen RM. de Waard AA, et al. Among authors: spaapen rm. Eur J Immunol. 2021 Mar;51(3):734-737. doi: 10.1002/eji.202048599. Epub 2021 Feb 1. Eur J Immunol. 2021. PMID: 33275281 Free PMC article.
Healthy cells functionally present TAP-independent SSR1 peptides: implications for selection of clinically relevant antigens.
de Waard AA, Verkerk T, Hoefakker K, van der Steen DM, Jongsma MLM, Melamed Kadosh D, Bliss S, de Ru AH, Admon A, van Veelen PA, Griffioen M, Heemskerk MHM, Spaapen RM. de Waard AA, et al. Among authors: spaapen rm. iScience. 2021 Jan 9;24(2):102051. doi: 10.1016/j.isci.2021.102051. eCollection 2021 Feb 19. iScience. 2021. PMID: 33554062 Free PMC article.
T Cells Specific for an Unconventional Natural Antigen Fail to Recognize Leukemic Cells.
Pont MJ, Oostvogels R, van Bergen CAM, van der Meijden ED, Honders MW, Bliss S, Jongsma MLM, Lokhorst HM, Falkenburg JHF, Mutis T, Griffioen M, Spaapen RM. Pont MJ, et al. Among authors: spaapen rm. Cancer Immunol Res. 2019 May;7(5):797-804. doi: 10.1158/2326-6066.CIR-18-0137. Epub 2019 Mar 19. Cancer Immunol Res. 2019. PMID: 30890530
The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses.
Jongsma MLM, de Waard AA, Raaben M, Zhang T, Cabukusta B, Platzer R, Blomen VA, Xagara A, Verkerk T, Bliss S, Kong X, Gerke C, Janssen L, Stickel E, Holst S, Plomp R, Mulder A, Ferrone S, Claas FHJ, Heemskerk MHM, Griffioen M, Halenius A, Overkleeft H, Huppa JB, Wuhrer M, Brummelkamp TR, Neefjes J, Spaapen RM. Jongsma MLM, et al. Among authors: spaapen rm. Immunity. 2021 Jan 12;54(1):132-150.e9. doi: 10.1016/j.immuni.2020.11.003. Epub 2020 Dec 2. Immunity. 2021. PMID: 33271119 Free PMC article.
Altered peptide ligands revisited: vaccine design through chemically modified HLA-A2-restricted T cell epitopes.
Hoppes R, Oostvogels R, Luimstra JJ, Wals K, Toebes M, Bies L, Ekkebus R, Rijal P, Celie PH, Huang JH, Emmelot ME, Spaapen RM, Lokhorst H, Schumacher TN, Mutis T, Rodenko B, Ovaa H. Hoppes R, et al. Among authors: spaapen rm. J Immunol. 2014 Nov 15;193(10):4803-13. doi: 10.4049/jimmunol.1400800. Epub 2014 Oct 13. J Immunol. 2014. PMID: 25311806 Free PMC article.
The regulatory network behind MHC class I expression.
Jongsma MLM, Guarda G, Spaapen RM. Jongsma MLM, et al. Among authors: spaapen rm. Mol Immunol. 2019 Sep;113:16-21. doi: 10.1016/j.molimm.2017.12.005. Epub 2017 Dec 8. Mol Immunol. 2019. PMID: 29224918 Free article. Review.
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