Pear WS - Search Results

1

Identifying direct Notch transcriptional targets using the GSI-washout assay.

Bailis W, Yashiro-Ohtani Y, Pear WS. Bailis W, et al. Among authors: pear ws. Methods Mol Biol. 2014;1187:247-54. doi: 10.1007/978-1-4939-1139-4_19. Methods Mol Biol. 2014. PMID: 25053495 Review.

2

Notch regulation of early thymocyte development.

Yashiro-Ohtani Y, Ohtani T, Pear WS. Yashiro-Ohtani Y, et al. Among authors: pear ws. Semin Immunol. 2010 Oct;22(5):261-9. doi: 10.1016/j.smim.2010.04.015. Epub 2010 Jul 13. Semin Immunol. 2010. PMID: 20630772 Review.

3

Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals.

Bailis W, Yashiro-Ohtani Y, Fang TC, Hatton RD, Weaver CT, Artis D, Pear WS. Bailis W, et al. Among authors: pear ws. Immunity. 2013 Jul 25;39(1):148-59. doi: 10.1016/j.immuni.2013.07.006. Immunity. 2013. PMID: 23890069 Free PMC article.

4

Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1.

Fragoso R, Mao T, Wang S, Schaffert S, Gong X, Yue S, Luong R, Min H, Yashiro-Ohtani Y, Davis M, Pear W, Chen CZ. Fragoso R, et al. PLoS Genet. 2012;8(8):e1002855. doi: 10.1371/journal.pgen.1002855. Epub 2012 Aug 9. PLoS Genet. 2012. PMID: 22916024 Free PMC article.

5

The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor.

Maillard I, Tu L, Sambandam A, Yashiro-Ohtani Y, Millholland J, Keeshan K, Shestova O, Xu L, Bhandoola A, Pear WS. Maillard I, et al. Among authors: pear ws. J Exp Med. 2006 Oct 2;203(10):2239-45. doi: 10.1084/jem.20061020. Epub 2006 Sep 11. J Exp Med. 2006. PMID: 16966428 Free PMC article.

6

Notch directly regulates Gata3 expression during T helper 2 cell differentiation.

Fang TC, Yashiro-Ohtani Y, Del Bianco C, Knoblock DM, Blacklow SC, Pear WS. Fang TC, et al. Among authors: pear ws. Immunity. 2007 Jul;27(1):100-10. doi: 10.1016/j.immuni.2007.04.018. Epub 2007 Jul 19. Immunity. 2007. PMID: 17658278 Free PMC article.

7

NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network.

Ohashi S, Natsuizaka M, Yashiro-Ohtani Y, Kalman RA, Nakagawa M, Wu L, Klein-Szanto AJ, Herlyn M, Diehl JA, Katz JP, Pear WS, Seykora JT, Nakagawa H. Ohashi S, et al. Among authors: pear ws. Gastroenterology. 2010 Dec;139(6):2113-23. doi: 10.1053/j.gastro.2010.08.040. Epub 2010 Aug 27. Gastroenterology. 2010. PMID: 20801121 Free PMC article.

8

Notch and PI3K: how is the road traveled?

Bailis W, Pear WS. Bailis W, et al. Among authors: pear ws. Blood. 2012 Aug 16;120(7):1349-50. doi: 10.1182/blood-2012-06-435099. Blood. 2012. PMID: 22899471 Free article.

9

T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.

De Obaldia ME, Bell JJ, Wang X, Harly C, Yashiro-Ohtani Y, DeLong JH, Zlotoff DA, Sultana DA, Pear WS, Bhandoola A. De Obaldia ME, et al. Among authors: pear ws. Nat Immunol. 2013 Dec;14(12):1277-84. doi: 10.1038/ni.2760. Epub 2013 Nov 3. Nat Immunol. 2013. PMID: 24185616 Free PMC article.

10

Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia.

Yashiro-Ohtani Y, Wang H, Zang C, Arnett KL, Bailis W, Ho Y, Knoechel B, Lanauze C, Louis L, Forsyth KS, Chen S, Chung Y, Schug J, Blobel GA, Liebhaber SA, Bernstein BE, Blacklow SC, Liu XS, Aster JC, Pear WS. Yashiro-Ohtani Y, et al. Among authors: pear ws. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):E4946-53. doi: 10.1073/pnas.1407079111. Epub 2014 Nov 4. Proc Natl Acad Sci U S A. 2014. PMID: 25369933 Free PMC article.

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