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Page 1
Workshop on acceleration of the validation and regulatory acceptance of alternative methods and implementation of testing strategies.
Piersma AH, Burgdorf T, Louekari K, Desprez B, Taalman R, Landsiedel R, Barroso J, Rogiers V, Eskes C, Oelgeschläger M, Whelan M, Braeuning A, Vinggaard AM, Kienhuis A, van Benthem J, Ezendam J. Piersma AH, et al. Among authors: van benthem j. Toxicol In Vitro. 2018 Aug;50:62-74. doi: 10.1016/j.tiv.2018.02.018. Epub 2018 Mar 2. Toxicol In Vitro. 2018. PMID: 29501630 Free article.
Reproductive toxicants have a threshold of adversity.
Piersma AH, Hernandez LG, van Benthem J, Muller JJ, van Leeuwen FX, Vermeire TG, van Raaij MT. Piersma AH, et al. Among authors: van leeuwen fx, van raaij mt, van benthem j. Crit Rev Toxicol. 2011 Jul;41(6):545-54. doi: 10.3109/10408444.2011.554794. Epub 2011 May 24. Crit Rev Toxicol. 2011. PMID: 21609253 Review.
An integrative test strategy for cancer hazard identification.
Luijten M, Olthof ED, Hakkert BC, Rorije E, van der Laan JW, Woutersen RA, van Benthem J. Luijten M, et al. Among authors: van der laan jw, van benthem j. Crit Rev Toxicol. 2016 Aug;46(7):615-39. doi: 10.3109/10408444.2016.1171294. Epub 2016 May 3. Crit Rev Toxicol. 2016. PMID: 27142259
Is current risk assessment of non-genotoxic carcinogens protective?
Braakhuis HM, Slob W, Olthof ED, Wolterink G, Zwart EP, Gremmer ER, Rorije E, van Benthem J, Woutersen R, van der Laan JW, Luijten M. Braakhuis HM, et al. Among authors: van der laan jw, van benthem j. Crit Rev Toxicol. 2018 Jul;48(6):500-511. doi: 10.1080/10408444.2018.1458818. Epub 2018 May 10. Crit Rev Toxicol. 2018. PMID: 29745287 Review.
Workshop on the validation and regulatory acceptance of innovative 3R approaches in regulatory toxicology - Evolution versus revolution.
Burgdorf T, Piersma AH, Landsiedel R, Clewell R, Kleinstreuer N, Oelgeschläger M, Desprez B, Kienhuis A, Bos P, de Vries R, de Wit L, Seidle T, Scheel J, Schönfelder G, van Benthem J, Vinggaard AM, Eskes C, Ezendam J. Burgdorf T, et al. Among authors: van benthem j. Toxicol In Vitro. 2019 Sep;59:1-11. doi: 10.1016/j.tiv.2019.03.039. Epub 2019 Apr 1. Toxicol In Vitro. 2019. PMID: 30946968
Detection of genotoxic and non-genotoxic carcinogens in Xpc(-/-)p53(+/-) mice.
Melis JP, Speksnijder EN, Kuiper RV, Salvatori DC, Schaap MM, Maas S, Robinson J, Verhoef A, van Benthem J, Luijten M, van Steeg H. Melis JP, et al. Among authors: van steeg h, van benthem j. Toxicol Appl Pharmacol. 2013 Jan 15;266(2):289-97. doi: 10.1016/j.taap.2012.11.004. Epub 2012 Nov 12. Toxicol Appl Pharmacol. 2013. PMID: 23153559
Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations.
Dearfield KL, Gollapudi BB, Bemis JC, Benz RD, Douglas GR, Elespuru RK, Johnson GE, Kirkland DJ, LeBaron MJ, Li AP, Marchetti F, Pottenger LH, Rorije E, Tanir JY, Thybaud V, van Benthem J, Yauk CL, Zeiger E, Luijten M. Dearfield KL, et al. Among authors: van benthem j. Environ Mol Mutagen. 2017 Jun;58(5):264-283. doi: 10.1002/em.22045. Epub 2016 Sep 21. Environ Mol Mutagen. 2017. PMID: 27650663 Review.
Validation redefined.
Piersma AH, van Benthem J, Ezendam J, Kienhuis AS. Piersma AH, et al. Among authors: van benthem j. Toxicol In Vitro. 2018 Feb;46:163-165. doi: 10.1016/j.tiv.2017.10.013. Epub 2017 Oct 9. Toxicol In Vitro. 2018. PMID: 29024777 No abstract available.
109 results