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Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial.
Holcomb JB, Tilley BC, Baraniuk S, Fox EE, Wade CE, Podbielski JM, del Junco DJ, Brasel KJ, Bulger EM, Callcut RA, Cohen MJ, Cotton BA, Fabian TC, Inaba K, Kerby JD, Muskat P, O'Keeffe T, Rizoli S, Robinson BR, Scalea TM, Schreiber MA, Stein DM, Weinberg JA, Callum JL, Hess JR, Matijevic N, Miller CN, Pittet JF, Hoyt DB, Pearson GD, Leroux B, van Belle G; PROPPR Study Group. Holcomb JB, et al. Among authors: rizoli s. JAMA. 2015 Feb 3;313(5):471-82. doi: 10.1001/jama.2015.12. JAMA. 2015. PMID: 25647203 Free PMC article. Clinical Trial.
Making thawed universal donor plasma available rapidly for massively bleeding trauma patients: experience from the Pragmatic, Randomized Optimal Platelets and Plasma Ratios (PROPPR) trial.
Novak DJ, Bai Y, Cooke RK, Marques MB, Fontaine MJ, Gottschall JL, Carey PM, Scanlan RM, Fiebig EW, Shulman IA, Nelson JM, Flax S, Duncan V, Daniel-Johnson JA, Callum JL, Holcomb JB, Fox EE, Baraniuk S, Tilley BC, Schreiber MA, Inaba K, Rizoli S, Podbielski JM, Cotton BA, Hess JR; PROPPR Study Group. Novak DJ, et al. Among authors: rizoli s. Transfusion. 2015 Jun;55(6):1331-9. doi: 10.1111/trf.13098. Epub 2015 Mar 30. Transfusion. 2015. PMID: 25823522 Free PMC article.
Group A emergency-release plasma in trauma patients requiring massive transfusion.
de Roulet A, Kerby JD, Weinberg JA, Lewis RH Jr, Hudgins JP, Shulman IA, Fox EE, Holcomb JB, Brasel KJ, Bulger EM, Cohen MJ, Cotton BA, Fabian TC, O'Keeffe T, Rizoli S, Scalea TM, Schreiber MA, Inaba K; PROPPR Study Group. de Roulet A, et al. Among authors: rizoli s. J Trauma Acute Care Surg. 2020 Dec;89(6):1061-1067. doi: 10.1097/TA.0000000000002903. J Trauma Acute Care Surg. 2020. PMID: 32890339 Free PMC article. Clinical Trial.
The hyperfibrinolytic phenotype is the most lethal and resource intense presentation of fibrinolysis in massive transfusion patients.
Taylor JR 3rd, Fox EE, Holcomb JB, Rizoli S, Inaba K, Schreiber MA, Brasel K, Scalea TM, Wade CE, Bulger E, Cotton BA; PROPPR Study Group. Taylor JR 3rd, et al. Among authors: rizoli s. J Trauma Acute Care Surg. 2018 Jan;84(1):25-30. doi: 10.1097/TA.0000000000001699. J Trauma Acute Care Surg. 2018. PMID: 28914713 Free PMC article. Clinical Trial.
Transfusion of red blood cells in patients with a prehospital Glasgow Coma Scale score of 8 or less and no evidence of shock is associated with worse outcomes.
Elterman J, Brasel K, Brown S, Bulger E, Christenson J, Kerby JD, Kannas D, Lin S, Minei JP, Rizoli S, Tisherman S, Schreiber MA; Resuscitation Outcomes Consortium Investigators. Elterman J, et al. Among authors: rizoli s. J Trauma Acute Care Surg. 2013 Jul;75(1):8-14; discussion 14. doi: 10.1097/TA.0b013e318298492e. J Trauma Acute Care Surg. 2013. PMID: 23778432 Free PMC article. Clinical Trial.
310 results