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Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy.
Gangadhariah MH, Luther JM, Garcia V, Paueksakon P, Zhang MZ, Hayward SW, Love HD, Falck JR, Manthati VL, Imig JD, Schwartzman ML, Zent R, Capdevila JH, Pozzi A. Gangadhariah MH, et al. Among authors: manthati vl. J Am Soc Nephrol. 2015 Mar;26(3):597-610. doi: 10.1681/ASN.2013090980. Epub 2014 Jul 28. J Am Soc Nephrol. 2015. PMID: 25071086 Free PMC article.
19-Hydroxyeicosatetraenoic acid analogs: Antagonism of 20-hydroxyeicosatetraenoic acid-induced vascular sensitization and hypertension.
Dakarapu R, Errabelli R, Manthati VL, Michael Adebesin A, Barma DK, Barma D, Garcia V, Zhang F, Laniado Schwartzman M, Falck JR. Dakarapu R, et al. Among authors: manthati vl. Bioorg Med Chem Lett. 2019 Oct 1;29(19):126616. doi: 10.1016/j.bmcl.2019.08.020. Epub 2019 Aug 13. Bioorg Med Chem Lett. 2019. PMID: 31439380 Free PMC article.
Development of epoxyeicosatrienoic acid analogs with in vivo anti-hypertensive actions.
Imig JD, Elmarakby A, Nithipatikom K, Wei S, Capdevila JH, Tuniki VR, Sangras B, Anjaiah S, Manthati VL, Sudarshan Reddy D, Falck JR. Imig JD, et al. Among authors: manthati vl. Front Physiol. 2010 Dec 3;1:157. doi: 10.3389/fphys.2010.00157. eCollection 2010. Front Physiol. 2010. PMID: 21423396 Free PMC article.
A synthetic epoxyeicosatrienoic acid analogue prevents the initiation of ischemic acute kidney injury.
Hoff U, Bubalo G, Fechner M, Blum M, Zhu Y, Pohlmann A, Hentschel J, Arakelyan K, Seeliger E, Flemming B, Gürgen D, Rothe M, Niendorf T, Manthati VL, Falck JR, Haase M, Schunck WH, Dragun D. Hoff U, et al. Among authors: manthati vl. Acta Physiol (Oxf). 2019 Oct;227(2):e13297. doi: 10.1111/apha.13297. Epub 2019 Jun 2. Acta Physiol (Oxf). 2019. PMID: 31077555 Free PMC article.
29 results