Dow LE - Search Results

1

p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer.

Tschaharganeh DF, Xue W, Calvisi DF, Evert M, Michurina TV, Dow LE, Banito A, Katz SF, Kastenhuber ER, Weissmueller S, Huang CH, Lechel A, Andersen JB, Capper D, Zender L, Longerich T, Enikolopov G, Lowe SW. Tschaharganeh DF, et al. Among authors: dow le. Cell. 2014 Jul 31;158(3):579-92. doi: 10.1016/j.cell.2014.05.051. Cell. 2014. PMID: 25083869 Free PMC article.

2

Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi.

Zuber J, McJunkin K, Fellmann C, Dow LE, Taylor MJ, Hannon GJ, Lowe SW. Zuber J, et al. Among authors: dow le. Nat Biotechnol. 2011 Jan;29(1):79-83. doi: 10.1038/nbt.1720. Epub 2010 Dec 5. Nat Biotechnol. 2011. PMID: 21131983 Free PMC article.

3

A rapid and scalable system for studying gene function in mice using conditional RNA interference.

Premsrirut PK, Dow LE, Kim SY, Camiolo M, Malone CD, Miething C, Scuoppo C, Zuber J, Dickins RA, Kogan SC, Shroyer KR, Sordella R, Hannon GJ, Lowe SW. Premsrirut PK, et al. Among authors: dow le. Cell. 2011 Apr 1;145(1):145-58. doi: 10.1016/j.cell.2011.03.012. Cell. 2011. PMID: 21458673 Free PMC article.

4

Reversible suppression of an essential gene in adult mice using transgenic RNA interference.

McJunkin K, Mazurek A, Premsrirut PK, Zuber J, Dow LE, Simon J, Stillman B, Lowe SW. McJunkin K, et al. Among authors: dow le. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7113-8. doi: 10.1073/pnas.1104097108. Epub 2011 Apr 11. Proc Natl Acad Sci U S A. 2011. PMID: 21482754 Free PMC article.

5

A pipeline for the generation of shRNA transgenic mice.

Dow LE, Premsrirut PK, Zuber J, Fellmann C, McJunkin K, Miething C, Park Y, Dickins RA, Hannon GJ, Lowe SW. Dow LE, et al. Nat Protoc. 2012 Feb 2;7(2):374-93. doi: 10.1038/nprot.2011.446. Nat Protoc. 2012. PMID: 22301776 Free PMC article.

6

Life in the fast lane: mammalian disease models in the genomics era.

Dow LE, Lowe SW. Dow LE, et al. Cell. 2012 Mar 16;148(6):1099-109. doi: 10.1016/j.cell.2012.02.023. Cell. 2012. PMID: 22424222 Free PMC article.

7

Creating transgenic shRNA mice by recombinase-mediated cassette exchange.

Premsrirut PK, Dow LE, Park Y, Hannon GJ, Lowe SW. Premsrirut PK, et al. Among authors: dow le. Cold Spring Harb Protoc. 2013 Sep 1;2013(9):835-42. doi: 10.1101/pdb.prot077057. Cold Spring Harb Protoc. 2013. PMID: 24003198 Free PMC article.

8

A modular and flexible ESC-based mouse model of pancreatic cancer.

Saborowski M, Saborowski A, Morris JP 4th, Bosbach B, Dow LE, Pelletier J, Klimstra DS, Lowe SW. Saborowski M, et al. Among authors: dow le. Genes Dev. 2014 Jan 1;28(1):85-97. doi: 10.1101/gad.232082.113. Genes Dev. 2014. PMID: 24395249 Free PMC article.

9

Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice.

Dow LE, Nasr Z, Saborowski M, Ebbesen SH, Manchado E, Tasdemir N, Lee T, Pelletier J, Lowe SW. Dow LE, et al. PLoS One. 2014 Apr 17;9(4):e95236. doi: 10.1371/journal.pone.0095236. eCollection 2014. PLoS One. 2014. PMID: 24743474 Free PMC article.

10

Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition.

Bolden JE, Tasdemir N, Dow LE, van Es JH, Wilkinson JE, Zhao Z, Clevers H, Lowe SW. Bolden JE, et al. Among authors: dow le. Cell Rep. 2014 Sep 25;8(6):1919-1929. doi: 10.1016/j.celrep.2014.08.025. Epub 2014 Sep 18. Cell Rep. 2014. PMID: 25242322 Free PMC article.

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