Wanker EE - Search Results

1

Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1.

Kayatekin C, Matlack KE, Hesse WR, Guan Y, Chakrabortee S, Russ J, Wanker EE, Shah JV, Lindquist S. Kayatekin C, et al. Among authors: wanker ee. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12085-90. doi: 10.1073/pnas.1412504111. Epub 2014 Aug 4. Proc Natl Acad Sci U S A. 2014. PMID: 25092318 Free PMC article.

2

Huntingtin aggregation monitored by dynamic light scattering.

Georgalis Y, Starikov EB, Hollenbach B, Lurz R, Scherzinger E, Saenger W, Lehrach H, Wanker EE. Georgalis Y, et al. Among authors: wanker ee. Proc Natl Acad Sci U S A. 1998 May 26;95(11):6118-21. doi: 10.1073/pnas.95.11.6118. Proc Natl Acad Sci U S A. 1998. PMID: 9600927 Free PMC article.

3

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates.

Sittler A, Wälter S, Wedemeyer N, Hasenbank R, Scherzinger E, Eickhoff H, Bates GP, Lehrach H, Wanker EE. Sittler A, et al. Among authors: wanker ee. Mol Cell. 1998 Oct;2(4):427-36. doi: 10.1016/s1097-2765(00)80142-2. Mol Cell. 1998. PMID: 9809064 Free article.

4

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology.

Scherzinger E, Sittler A, Schweiger K, Heiser V, Lurz R, Hasenbank R, Bates GP, Lehrach H, Wanker EE. Scherzinger E, et al. Among authors: wanker ee. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4604-9. doi: 10.1073/pnas.96.8.4604. Proc Natl Acad Sci U S A. 1999. PMID: 10200309 Free PMC article.

5

Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy.

Heiser V, Scherzinger E, Boeddrich A, Nordhoff E, Lurz R, Schugardt N, Lehrach H, Wanker EE. Heiser V, et al. Among authors: wanker ee. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6739-44. doi: 10.1073/pnas.110138997. Proc Natl Acad Sci U S A. 2000. PMID: 10829068 Free PMC article.

6

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils.

Muchowski PJ, Schaffar G, Sittler A, Wanker EE, Hayer-Hartl MK, Hartl FU. Muchowski PJ, et al. Among authors: wanker ee. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7841-6. doi: 10.1073/pnas.140202897. Proc Natl Acad Sci U S A. 2000. PMID: 10859365 Free PMC article.

7

Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid beta-peptide of amyloid plaques.

Perutz MF, Pope BJ, Owen D, Wanker EE, Scherzinger E. Perutz MF, et al. Among authors: wanker ee. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5596-600. doi: 10.1073/pnas.042681599. Proc Natl Acad Sci U S A. 2002. PMID: 11960015 Free PMC article.

8

Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay.

Heiser V, Engemann S, Bröcker W, Dunkel I, Boeddrich A, Waelter S, Nordhoff E, Lurz R, Schugardt N, Rautenberg S, Herhaus C, Barnickel G, Böttcher H, Lehrach H, Wanker EE. Heiser V, et al. Among authors: wanker ee. Proc Natl Acad Sci U S A. 2002 Dec 10;99 Suppl 4(Suppl 4):16400-6. doi: 10.1073/pnas.182426599. Epub 2002 Aug 28. Proc Natl Acad Sci U S A. 2002. PMID: 12200548 Free PMC article.

9

Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease.

Busch A, Engemann S, Lurz R, Okazawa H, Lehrach H, Wanker EE. Busch A, et al. Among authors: wanker ee. J Biol Chem. 2003 Oct 17;278(42):41452-61. doi: 10.1074/jbc.M303354200. Epub 2003 Jul 29. J Biol Chem. 2003. PMID: 12888569 Free article.

10

The hunt for huntingtin function: interaction partners tell many different stories.

Harjes P, Wanker EE. Harjes P, et al. Among authors: wanker ee. Trends Biochem Sci. 2003 Aug;28(8):425-33. doi: 10.1016/S0968-0004(03)00168-3. Trends Biochem Sci. 2003. PMID: 12932731 Review.

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