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The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.
Lucas JM, Heinlein C, Kim T, Hernandez SA, Malik MS, True LD, Morrissey C, Corey E, Montgomery B, Mostaghel E, Clegg N, Coleman I, Brown CM, Schneider EL, Craik C, Simon JA, Bedalov A, Nelson PS. Lucas JM, et al. Among authors: clegg n. Cancer Discov. 2014 Nov;4(11):1310-25. doi: 10.1158/2159-8290.CD-13-1010. Epub 2014 Aug 13. Cancer Discov. 2014. PMID: 25122198 Free PMC article.
A neuroendocrine/small cell prostate carcinoma xenograft-LuCaP 49.
True LD, Buhler K, Quinn J, Williams E, Nelson PS, Clegg N, Macoska JA, Norwood T, Liu A, Ellis W, Lange P, Vessella R. True LD, et al. Among authors: clegg n. Am J Pathol. 2002 Aug;161(2):705-15. doi: 10.1016/S0002-9440(10)64226-5. Am J Pathol. 2002. PMID: 12163395 Free PMC article.
The program of androgen-responsive genes in neoplastic prostate epithelium.
Nelson PS, Clegg N, Arnold H, Ferguson C, Bonham M, White J, Hood L, Lin B. Nelson PS, et al. Among authors: clegg n. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11890-5. doi: 10.1073/pnas.182376299. Epub 2002 Aug 16. Proc Natl Acad Sci U S A. 2002. PMID: 12185249 Free PMC article.
75 results