Gangjee A - Search Results

1

Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase.

Kumar VP, Cisneros JA, Frey KM, Castellanos-Gonzalez A, Wang Y, Gangjee A, White AC Jr, Jorgensen WL, Anderson KS. Kumar VP, et al. Among authors: gangjee a. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4158-61. doi: 10.1016/j.bmcl.2014.07.049. Epub 2014 Jul 24. Bioorg Med Chem Lett. 2014. PMID: 25127103 Free PMC article.

2

5,10-Methylenetetrahydro-5-deazafolic acid and analogues: synthesis and biological activities.

Gangjee A, Patel J, Kisliuk RL, Gaumont Y. Gangjee A, et al. J Med Chem. 1992 Oct 2;35(20):3678-85. doi: 10.1021/jm00098a013. J Med Chem. 1992. PMID: 1433179

3

Synthesis and biological activity of 5,11-methylenetetrahydro-5- deazahomofolic acid.

Gangjee A, Donkor IO, Kisliuk RL, Gaumont Y, Thorndike J. Gangjee A, et al. J Med Chem. 1991 Feb;34(2):611-6. doi: 10.1021/jm00106a022. J Med Chem. 1991. PMID: 1995884

4

5-Arylthio-substituted 2-amino-4-oxo-6-methylpyrrolo[2,3-d]pyrimidine antifolates as thymidylate synthase inhibitors and antitumor agents.

Gangjee A, Devraj R, McGuire JJ, Kisliuk RL. Gangjee A, et al. J Med Chem. 1995 Oct 27;38(22):4495-502. doi: 10.1021/jm00022a015. J Med Chem. 1995. PMID: 7473577

5

Effect of bridge region variation on antifolate and antitumor activity of classical 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines.

Gangjee A, Devraj R, McGuire JJ, Kisliuk RL. Gangjee A, et al. J Med Chem. 1995 Sep 15;38(19):3798-805. doi: 10.1021/jm00019a009. J Med Chem. 1995. PMID: 7562910

6

Nonclassical 2,4-diamino-6-(aminomethyl)-5,6,7,8-tetrahydroquinazoline antifolates: synthesis and biological activities.

Gangjee A, Zaveri N, Kothare M, Queener SF. Gangjee A, et al. J Med Chem. 1995 Sep 1;38(18):3660-8. doi: 10.1021/jm00018a027. J Med Chem. 1995. PMID: 7658454

7

6-substituted 2,4-diamino-5-methylpyrido[2,3-d]pyrimidines as inhibitors of dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents.

Gangjee A, Vasudevan A, Queener SF, Kisliuk RL. Gangjee A, et al. J Med Chem. 1995 May 12;38(10):1778-85. doi: 10.1021/jm00010a022. J Med Chem. 1995. PMID: 7752201

8

Novel 2,4-diamino-5-substituted-pyrrolo[2,3-d]pyrimidines as classical and nonclassical antifolate inhibitors of dihydrofolate reductases.

Gangjee A, Mavandadi F, Queener SF, McGuire JJ. Gangjee A, et al. J Med Chem. 1995 Jun 9;38(12):2158-65. doi: 10.1021/jm00012a016. J Med Chem. 1995. PMID: 7783147

9

Classical and nonclassical furo[2,3-d]pyrimidines as novel antifolates: synthesis and biological activities.

Gangjee A, Devraj R, McGuire JJ, Kisliuk RL, Queener SF, Barrows LR. Gangjee A, et al. J Med Chem. 1994 Apr 15;37(8):1169-76. doi: 10.1021/jm00034a015. J Med Chem. 1994. PMID: 8164259

10

Synthesis of 5-methyl-5-deaza nonclassical antifolates as inhibitors of dihydrofolate reductases and as potential antipneumocystis, antitoxoplasma, and antitumor agents.

Gangjee A, Shi J, Queener SF, Barrows LR, Kisliuk RL. Gangjee A, et al. J Med Chem. 1993 Oct 29;36(22):3437-43. doi: 10.1021/jm00074a026. J Med Chem. 1993. PMID: 8230134

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