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Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
Hermann PC, Sancho P, Cañamero M, Martinelli P, Madriles F, Michl P, Gress T, de Pascual R, Gandia L, Guerra C, Barbacid M, Wagner M, Vieira CR, Aicher A, Real FX, Sainz B Jr, Heeschen C. Hermann PC, et al. Among authors: sancho p. Gastroenterology. 2014 Nov;147(5):1119-33.e4. doi: 10.1053/j.gastro.2014.08.002. Epub 2014 Aug 12. Gastroenterology. 2014. PMID: 25127677
Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment.
Sainz B Jr, Alcala S, Garcia E, Sanchez-Ripoll Y, Azevedo MM, Cioffi M, Tatari M, Miranda-Lorenzo I, Hidalgo M, Gomez-Lopez G, Cañamero M, Erkan M, Kleeff J, García-Silva S, Sancho P, Hermann PC, Heeschen C. Sainz B Jr, et al. Among authors: sancho p. Gut. 2015 Dec;64(12):1921-35. doi: 10.1136/gutjnl-2014-308935. Epub 2015 Apr 3. Gut. 2015. PMID: 25841238
The ever-changing landscape of pancreatic cancer stem cells.
Sancho P, Alcala S, Usachov V, Hermann PC, Sainz B Jr. Sancho P, et al. Pancreatology. 2016 Jul-Aug;16(4):489-96. doi: 10.1016/j.pan.2016.04.004. Epub 2016 Apr 14. Pancreatology. 2016. PMID: 27161173 Review.
Hallmarks of cancer stem cell metabolism.
Sancho P, Barneda D, Heeschen C. Sancho P, et al. Br J Cancer. 2016 Jun 14;114(12):1305-12. doi: 10.1038/bjc.2016.152. Epub 2016 May 24. Br J Cancer. 2016. PMID: 27219018 Free PMC article. Review.
ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity.
Alcalá S, Sancho P, Martinelli P, Navarro D, Pedrero C, Martín-Hijano L, Valle S, Earl J, Rodríguez-Serrano M, Ruiz-Cañas L, Rojas K, Carrato A, García-Bermejo L, Fernández-Moreno MÁ, Hermann PC, Sainz B Jr. Alcalá S, et al. Among authors: sancho p. Nat Commun. 2020 May 29;11(1):2682. doi: 10.1038/s41467-020-16395-2. Nat Commun. 2020. PMID: 32472071 Free PMC article.
Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells.
Valle S, Alcalá S, Martin-Hijano L, Cabezas-Sáinz P, Navarro D, Muñoz ER, Yuste L, Tiwary K, Walter K, Ruiz-Cañas L, Alonso-Nocelo M, Rubiolo JA, González-Arnay E, Heeschen C, Garcia-Bermejo L, Hermann PC, Sánchez L, Sancho P, Fernández-Moreno MÁ, Sainz B Jr. Valle S, et al. Among authors: sancho p. Nat Commun. 2020 Oct 16;11(1):5265. doi: 10.1038/s41467-020-18954-z. Nat Commun. 2020. PMID: 33067432 Free PMC article.
161 results