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Page 1
Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis.
Annibali D, Whitfield JR, Favuzzi E, Jauset T, Serrano E, Cuartas I, Redondo-Campos S, Folch G, Gonzàlez-Juncà A, Sodir NM, Massó-Vallés D, Beaulieu ME, Swigart LB, Mc Gee MM, Somma MP, Nasi S, Seoane J, Evan GI, Soucek L. Annibali D, et al. Among authors: gonzalez junca a. Nat Commun. 2014 Aug 18;5:4632. doi: 10.1038/ncomms5632. Nat Commun. 2014. PMID: 25130259 Free PMC article.
TGF-β Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma.
Anido J, Sáez-Borderías A, Gonzàlez-Juncà A, Rodón L, Folch G, Carmona MA, Prieto-Sánchez RM, Barba I, Martínez-Sáez E, Prudkin L, Cuartas I, Raventós C, Martínez-Ricarte F, Poca MA, García-Dorado D, Lahn MM, Yingling JM, Rodón J, Sahuquillo J, Baselga J, Seoane J. Anido J, et al. Cancer Cell. 2010 Dec 14;18(6):655-68. doi: 10.1016/j.ccr.2010.10.023. Cancer Cell. 2010. PMID: 21156287 Free article.
USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma.
Eichhorn PJ, Rodón L, Gonzàlez-Juncà A, Dirac A, Gili M, Martínez-Sáez E, Aura C, Barba I, Peg V, Prat A, Cuartas I, Jimenez J, García-Dorado D, Sahuquillo J, Bernards R, Baselga J, Seoane J. Eichhorn PJ, et al. Among authors: gonzalez junca a. Nat Med. 2012 Feb 19;18(3):429-35. doi: 10.1038/nm.2619. Nat Med. 2012. PMID: 22344298
Active CREB1 promotes a malignant TGFβ2 autocrine loop in glioblastoma.
Rodón L, Gonzàlez-Juncà A, Inda Mdel M, Sala-Hojman A, Martínez-Sáez E, Seoane J. Rodón L, et al. Among authors: gonzalez junca a. Cancer Discov. 2014 Oct;4(10):1230-41. doi: 10.1158/2159-8290.CD-14-0275. Epub 2014 Aug 1. Cancer Discov. 2014. PMID: 25084773
Blockade of the SNARE protein syntaxin 1 inhibits glioblastoma tumor growth.
Ulloa F, Gonzàlez-Juncà A, Meffre D, Barrecheguren PJ, Martínez-Mármol R, Pazos I, Olivé N, Cotrufo T, Seoane J, Soriano E. Ulloa F, et al. Among authors: gonzalez junca a. PLoS One. 2015 Mar 24;10(3):e0119707. doi: 10.1371/journal.pone.0119707. eCollection 2015. PLoS One. 2015. PMID: 25803850 Free PMC article.
Inflammation Mediates the Development of Aggressive Breast Cancer Following Radiotherapy.
Ma L, Gonzalez-Junca A, Zheng Y, Ouyang H, Illa-Bochaca I, Horst KC, Krings G, Wang Y, Fernandez-Garcia I, Chou W, Barcellos-Hoff MH. Ma L, et al. Among authors: gonzalez junca a. Clin Cancer Res. 2021 Mar 15;27(6):1778-1791. doi: 10.1158/1078-0432.CCR-20-3215. Epub 2021 Jan 5. Clin Cancer Res. 2021. PMID: 33402361 Free PMC article.
Positron Emission Tomography Imaging of Functional Transforming Growth Factor β (TGFβ) Activity and Benefit of TGFβ Inhibition in Irradiated Intracranial Tumors.
Gonzalez-Junca A, Reiners O, Borrero-Garcia LD, Beckford-Vera D, Lazar AA, Chou W, Braunstein S, VanBrocklin H, Franc BL, Barcellos-Hoff MH. Gonzalez-Junca A, et al. Int J Radiat Oncol Biol Phys. 2021 Feb 1;109(2):527-539. doi: 10.1016/j.ijrobp.2020.09.043. Epub 2020 Sep 29. Int J Radiat Oncol Biol Phys. 2021. PMID: 33007434 Free PMC article.
SENTI-101, a Preparation of Mesenchymal Stromal Cells Engineered to Express IL12 and IL21, Induces Localized and Durable Antitumor Immunity in Preclinical Models of Peritoneal Solid Tumors.
Gonzalez-Junca A, Liu FD, Nagaraja AS, Mullenix A, Lee CT, Gordley RM, Frimannsson DO, Maller O, Garrison BS, Iyer D, Benabbas A, Truong TA, Quach A, Tian M, Martinez R, Savur R, Perry-McNamara A, Nguyen D, Almudhfar N, Blanco C, Huynh C, Nand A, Lay YE, Magal A, Mangalampalli S, Lee PJ, Lu TK, Lee G. Gonzalez-Junca A, et al. Mol Cancer Ther. 2021 Sep;20(9):1508-1520. doi: 10.1158/1535-7163.MCT-21-0030. Epub 2021 Jul 1. Mol Cancer Ther. 2021. PMID: 34210826
11 results