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In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers.
Watanabe S, Hayashi K, Toh K, Kim HJ, Liu X, Chaya H, Fukushima S, Katsushima K, Kondo Y, Uchida S, Ogura S, Nomoto T, Takemoto H, Cabral H, Kinoh H, Tanaka HY, Kano MR, Matsumoto Y, Fukuhara H, Uchida S, Nangaku M, Osada K, Nishiyama N, Miyata K, Kataoka K. Watanabe S, et al. Among authors: chaya h. Nat Commun. 2019 Apr 24;10(1):1894. doi: 10.1038/s41467-019-09856-w. Nat Commun. 2019. PMID: 31019193 Free PMC article.
Noncovalent Stabilization of Vesicular Polyion Complexes with Chemically Modified/Single-Stranded Oligonucleotides and PEG-b-guanidinylated Polypeptides for Intracavity Encapsulation of Effector Enzymes Aimed at Cooperative Gene Knockdown.
Kim BS, Naito M, Chaya H, Hori M, Hayashi K, Min HS, Yi Y, Kim HJ, Nagata T, Anraku Y, Kishimura A, Kataoka K, Miyata K. Kim BS, et al. Among authors: chaya h. Biomacromolecules. 2020 Oct 12;21(10):4365-4376. doi: 10.1021/acs.biomac.0c01192. Epub 2020 Sep 23. Biomacromolecules. 2020. PMID: 32924444
Pharmacokinetic and Pharmacodynamic Profiles of Glyco-Modified Atrial Natriuretic Peptide Derivatives Synthesized Using Chemo-enzymatic Synthesis Approaches.
Iwamoto M, Yamaguchi T, Sekiguchi Y, Oishi S, Shiiki T, Soma M, Nakamura K, Yoshida M, Chaya H, Mori Y, Miyauchi R, Hasegawa J, Nagayama T, Honda T. Iwamoto M, et al. Among authors: chaya h. Bioconjug Chem. 2018 Aug 15;29(8):2829-2837. doi: 10.1021/acs.bioconjchem.8b00427. Epub 2018 Aug 3. Bioconjug Chem. 2018. PMID: 30107743
11 results