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Mouse models of the fragile X premutation and fragile X-associated tremor/ataxia syndrome.
Berman RF, Buijsen RA, Usdin K, Pintado E, Kooy F, Pretto D, Pessah IN, Nelson DL, Zalewski Z, Charlet-Bergeurand N, Willemsen R, Hukema RK. Berman RF, et al. Among authors: hukema rk. J Neurodev Disord. 2014;6(1):25. doi: 10.1186/1866-1955-6-25. Epub 2014 Jul 30. J Neurodev Disord. 2014. PMID: 25136376 Free PMC article. Review.
Widespread non-central nervous system organ pathology in fragile X premutation carriers with fragile X-associated tremor/ataxia syndrome and CGG knock-in mice.
Hunsaker MR, Greco CM, Spath MA, Smits AP, Navarro CS, Tassone F, Kros JM, Severijnen LA, Berry-Kravis EM, Berman RF, Hagerman PJ, Willemsen R, Hagerman RJ, Hukema RK. Hunsaker MR, et al. Among authors: hukema rk. Acta Neuropathol. 2011 Oct;122(4):467-79. doi: 10.1007/s00401-011-0860-9. Epub 2011 Jul 23. Acta Neuropathol. 2011. PMID: 21785977 Free PMC article.
Reversibility of neuropathology and motor deficits in an inducible mouse model for FXTAS.
Hukema RK, Buijsen RA, Schonewille M, Raske C, Severijnen LA, Nieuwenhuizen-Bakker I, Verhagen RF, van Dessel L, Maas A, Charlet-Berguerand N, De Zeeuw CI, Hagerman PJ, Berman RF, Willemsen R. Hukema RK, et al. Hum Mol Genet. 2015 Sep 1;24(17):4948-57. doi: 10.1093/hmg/ddv216. Epub 2015 Jun 9. Hum Mol Genet. 2015. PMID: 26060190 Free PMC article.
The quest for targeted therapy in fragile X syndrome.
Zeidler S, Hukema RK, Willemsen R. Zeidler S, et al. Among authors: hukema rk. Expert Opin Ther Targets. 2015;19(10):1277-81. doi: 10.1517/14728222.2015.1079176. Epub 2015 Aug 14. Expert Opin Ther Targets. 2015. PMID: 26294013
41 results