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FoxM1, a critical regulator of oxidative stress during oncogenesis.
Park HJ, Carr JR, Wang Z, Nogueira V, Hay N, Tyner AL, Lau LF, Costa RH, Raychaudhuri P. Park HJ, et al. Among authors: wang z. EMBO J. 2009 Oct 7;28(19):2908-18. doi: 10.1038/emboj.2009.239. Epub 2009 Aug 20. EMBO J. 2009. PMID: 19696738 Free PMC article.
Deregulation of FoxM1b leads to tumour metastasis.
Park HJ, Gusarova G, Wang Z, Carr JR, Li J, Kim KH, Qiu J, Park YD, Williamson PR, Hay N, Tyner AL, Lau LF, Costa RH, Raychaudhuri P. Park HJ, et al. Among authors: wang z. EMBO Mol Med. 2011 Jan;3(1):21-34. doi: 10.1002/emmm.201000107. Epub 2010 Dec 17. EMBO Mol Med. 2011. PMID: 21204266 Free PMC article.
Targeting FoxM1 effectively retards p53-null lymphoma and sarcoma.
Wang Z, Zheng Y, Park HJ, Li J, Carr JR, Chen YJ, Kiefer MM, Kopanja D, Bagchi S, Tyner AL, Raychaudhuri P. Wang Z, et al. Mol Cancer Ther. 2013 May;12(5):759-67. doi: 10.1158/1535-7163.MCT-12-0903. Epub 2013 Feb 20. Mol Cancer Ther. 2013. PMID: 23427295 Free PMC article.
FoxM1 regulates mammary luminal cell fate.
Carr JR, Kiefer MM, Park HJ, Li J, Wang Z, Fontanarosa J, DeWaal D, Kopanja D, Benevolenskaya EV, Guzman G, Raychaudhuri P. Carr JR, et al. Among authors: wang z. Cell Rep. 2012 Jun 28;1(6):715-29. doi: 10.1016/j.celrep.2012.05.005. Epub 2012 Jun 7. Cell Rep. 2012. PMID: 22813746 Free PMC article.
Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer.
Patra KC, Wang Q, Bhaskar PT, Miller L, Wang Z, Wheaton W, Chandel N, Laakso M, Muller WJ, Allen EL, Jha AK, Smolen GA, Clasquin MF, Robey B, Hay N. Patra KC, et al. Among authors: wang z, wang q. Cancer Cell. 2013 Aug 12;24(2):213-228. doi: 10.1016/j.ccr.2013.06.014. Epub 2013 Aug 1. Cancer Cell. 2013. PMID: 23911236 Free PMC article.
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