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Rationally designed less toxic SPD-304 analogs and preliminary evaluation of their TNF inhibitory effects.
Arch Pharm (Weinheim). 2014 Nov;347(11):798-805. doi: 10.1002/ardp.201400198. Epub 2014 Aug 27.
Arch Pharm (Weinheim). 2014.
PMID: 25160057
Aqueous Solubility Enhancement for Bioassays of Insoluble Inhibitors and QSPR Analysis: A TNF-α Study.
Mettou A, Papaneophytou C, Melagraki G, Maranti A, Liepouri F, Alexiou P, Papakyriakou A, Couladouros E, Eliopoulos E, Afantitis A, Kontopidis G.
Mettou A, et al.
SLAS Discov. 2018 Jan;23(1):84-93. doi: 10.1177/2472555217712507. Epub 2017 Jun 6.
SLAS Discov. 2018.
PMID: 28586633
Free article.
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Solvent Selection for Insoluble Ligands, a Challenge for Biological Assay Development: A TNF-α/SPD304 Study.
Papaneophytou CP, Mettou AK, Rinotas V, Douni E, Kontopidis GA.
Papaneophytou CP, et al. Among authors: mettou ak.
ACS Med Chem Lett. 2012 Nov 29;4(1):137-41. doi: 10.1021/ml300380h. eCollection 2013 Jan 10.
ACS Med Chem Lett. 2012.
PMID: 24900576
Free PMC article.
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