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Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.
Rankin EB, Fuh KC, Castellini L, Viswanathan K, Finger EC, Diep AN, LaGory EL, Kariolis MS, Chan A, Lindgren D, Axelson H, Miao YR, Krieg AJ, Giaccia AJ. Rankin EB, et al. Among authors: giaccia aj. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13373-8. doi: 10.1073/pnas.1404848111. Epub 2014 Sep 3. Proc Natl Acad Sci U S A. 2014. PMID: 25187556 Free PMC article.
AXL is an essential factor and therapeutic target for metastatic ovarian cancer.
Rankin EB, Fuh KC, Taylor TE, Krieg AJ, Musser M, Yuan J, Wei K, Kuo CJ, Longacre TA, Giaccia AJ. Rankin EB, et al. Among authors: giaccia aj. Cancer Res. 2010 Oct 1;70(19):7570-9. doi: 10.1158/0008-5472.CAN-10-1267. Epub 2010 Sep 21. Cancer Res. 2010. PMID: 20858715 Free PMC article.
VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration.
Razorenova OV, Finger EC, Colavitti R, Chernikova SB, Boiko AD, Chan CK, Krieg A, Bedogni B, LaGory E, Weissman IL, Broome-Powell M, Giaccia AJ. Razorenova OV, et al. Among authors: giaccia aj. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):1931-6. doi: 10.1073/pnas.1011777108. Epub 2011 Jan 13. Proc Natl Acad Sci U S A. 2011. PMID: 21233420 Free PMC article.
Hypoxic control of metastasis.
Rankin EB, Giaccia AJ. Rankin EB, et al. Among authors: giaccia aj. Science. 2016 Apr 8;352(6282):175-80. doi: 10.1126/science.aaf4405. Epub 2016 Apr 7. Science. 2016. PMID: 27124451 Free PMC article. Review.
Hypoxia: Signaling the Metastatic Cascade.
Rankin EB, Nam JM, Giaccia AJ. Rankin EB, et al. Among authors: giaccia aj. Trends Cancer. 2016 Jun;2(6):295-304. doi: 10.1016/j.trecan.2016.05.006. Epub 2016 Jun 2. Trends Cancer. 2016. PMID: 28741527 Free PMC article. Review.
344 results