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The developmental potential of iPSCs is greatly influenced by reprogramming factor selection.
Buganim Y, Markoulaki S, van Wietmarschen N, Hoke H, Wu T, Ganz K, Akhtar-Zaidi B, He Y, Abraham BJ, Porubsky D, Kulenkampff E, Faddah DA, Shi L, Gao Q, Sarkar S, Cohen M, Goldmann J, Nery JR, Schultz MD, Ecker JR, Xiao A, Young RA, Lansdorp PM, Jaenisch R. Buganim Y, et al. Among authors: lansdorp pm. Cell Stem Cell. 2014 Sep 4;15(3):295-309. doi: 10.1016/j.stem.2014.07.003. Cell Stem Cell. 2014. PMID: 25192464 Free PMC article.
Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies.
Bakker B, Taudt A, Belderbos ME, Porubsky D, Spierings DC, de Jong TV, Halsema N, Kazemier HG, Hoekstra-Wakker K, Bradley A, de Bont ES, van den Berg A, Guryev V, Lansdorp PM, Colomé-Tatché M, Foijer F. Bakker B, et al. Among authors: lansdorp pm. Genome Biol. 2016 May 31;17(1):115. doi: 10.1186/s13059-016-0971-7. Genome Biol. 2016. PMID: 27246460 Free PMC article.
Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons.
van den Bos H, Spierings DC, Taudt AS, Bakker B, Porubský D, Falconer E, Novoa C, Halsema N, Kazemier HG, Hoekstra-Wakker K, Guryev V, den Dunnen WF, Foijer F, Tatché MC, Boddeke HW, Lansdorp PM. van den Bos H, et al. Among authors: lansdorp pm. Genome Biol. 2016 May 31;17(1):116. doi: 10.1186/s13059-016-0976-2. Genome Biol. 2016. PMID: 27246599 Free PMC article.
Direct chromosome-length haplotyping by single-cell sequencing.
Porubský D, Sanders AD, van Wietmarschen N, Falconer E, Hills M, Spierings DC, Bevova MR, Guryev V, Lansdorp PM. Porubský D, et al. Among authors: lansdorp pm. Genome Res. 2016 Nov;26(11):1565-1574. doi: 10.1101/gr.209841.116. Epub 2016 Sep 19. Genome Res. 2016. PMID: 27646535 Free PMC article.
313 results