Xie C - Search Results

1

Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export.

Cho HJ, Yu J, Xie C, Rudrabhatla P, Chen X, Wu J, Parisiadou L, Liu G, Sun L, Ma B, Ding J, Liu Z, Cai H. Cho HJ, et al. Among authors: xie c. EMBO J. 2014 Oct 16;33(20):2314-31. doi: 10.15252/embj.201487807. Epub 2014 Sep 8. EMBO J. 2014. PMID: 25201882 Free PMC article.

2

Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein.

Lin X, Parisiadou L, Gu XL, Wang L, Shim H, Sun L, Xie C, Long CX, Yang WJ, Ding J, Chen ZZ, Gallant PE, Tao-Cheng JH, Rudow G, Troncoso JC, Liu Z, Li Z, Cai H. Lin X, et al. Among authors: xie c. Neuron. 2009 Dec 24;64(6):807-27. doi: 10.1016/j.neuron.2009.11.006. Neuron. 2009. PMID: 20064389 Free PMC article.

3

MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein.

Cho HJ, Liu G, Jin SM, Parisiadou L, Xie C, Yu J, Sun L, Ma B, Ding J, Vancraenenbroeck R, Lobbestael E, Baekelandt V, Taymans JM, He P, Troncoso JC, Shen Y, Cai H. Cho HJ, et al. Among authors: xie c. Hum Mol Genet. 2013 Feb 1;22(3):608-20. doi: 10.1093/hmg/dds470. Epub 2012 Nov 2. Hum Mol Genet. 2013. PMID: 23125283 Free PMC article.

4

LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity.

Parisiadou L, Yu J, Sgobio C, Xie C, Liu G, Sun L, Gu XL, Lin X, Crowley NA, Lovinger DM, Cai H. Parisiadou L, et al. Among authors: xie c. Nat Neurosci. 2014 Mar;17(3):367-76. doi: 10.1038/nn.3636. Epub 2014 Jan 26. Nat Neurosci. 2014. PMID: 24464040 Free PMC article.

5

Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.

Liu G, Sgobio C, Gu X, Sun L, Lin X, Yu J, Parisiadou L, Xie C, Sastry N, Ding J, Lohr KM, Miller GW, Mateo Y, Lovinger DM, Cai H. Liu G, et al. Among authors: xie c. Hum Mol Genet. 2015 Sep 15;24(18):5299-312. doi: 10.1093/hmg/ddv249. Epub 2015 Jun 29. Hum Mol Genet. 2015. PMID: 26123485 Free PMC article.

6

LRRK2 modulates microglial activity through regulation of chemokine (C-X3-C) receptor 1 -mediated signalling pathways.

Ma B, Xu L, Pan X, Sun L, Ding J, Xie C, Koliatsos VE, Cai H. Ma B, et al. Among authors: xie c. Hum Mol Genet. 2016 Aug 15;25(16):3515-3523. doi: 10.1093/hmg/ddw194. Epub 2016 Jul 4. Hum Mol Genet. 2016. PMID: 27378696 Free PMC article.

7

Parkinson's disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging.

Chen X, Xie C, Tian W, Sun L, Zheng W, Hawes S, Chang L, Kung J, Ding J, Chen S, Le W, Cai H. Chen X, et al. Among authors: xie c. Mol Neurodegener. 2020 Feb 19;15(1):12. doi: 10.1186/s13024-020-00360-0. Mol Neurodegener. 2020. PMID: 32075681 Free PMC article.

8

The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2.

Wang L, Xie C, Greggio E, Parisiadou L, Shim H, Sun L, Chandran J, Lin X, Lai C, Yang WJ, Moore DJ, Dawson TM, Dawson VL, Chiosis G, Cookson MR, Cai H. Wang L, et al. Among authors: xie c. J Neurosci. 2008 Mar 26;28(13):3384-91. doi: 10.1523/JNEUROSCI.0185-08.2008. J Neurosci. 2008. PMID: 18367605 Free PMC article.

9

Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis.

Parisiadou L, Xie C, Cho HJ, Lin X, Gu XL, Long CX, Lobbestael E, Baekelandt V, Taymans JM, Sun L, Cai H. Parisiadou L, et al. Among authors: xie c. J Neurosci. 2009 Nov 4;29(44):13971-80. doi: 10.1523/JNEUROSCI.3799-09.2009. J Neurosci. 2009. PMID: 19890007 Free PMC article.

10

A calcineurin- and NFAT-dependent pathway is involved in α-synuclein-induced degeneration of midbrain dopaminergic neurons.

Luo J, Sun L, Lin X, Liu G, Yu J, Parisiadou L, Xie C, Ding J, Cai H. Luo J, et al. Among authors: xie c. Hum Mol Genet. 2014 Dec 15;23(24):6567-74. doi: 10.1093/hmg/ddu377. Epub 2014 Jul 22. Hum Mol Genet. 2014. PMID: 25051958 Free PMC article.

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