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Direct binding of Bcl-2 family proteins by quercetin triggers its pro-apoptotic activity.
Primikyri A, Chatziathanasiadou MV, Karali E, Kostaras E, Mantzaris MD, Hatzimichael E, Shin JS, Chi SW, Briasoulis E, Kolettas E, Gerothanassis IP, Tzakos AG. Primikyri A, et al. Among authors: shin js. ACS Chem Biol. 2014 Dec 19;9(12):2737-41. doi: 10.1021/cb500259e. Epub 2014 Oct 9. ACS Chem Biol. 2014. PMID: 25211642
Structural insights into the dual-targeting mechanism of Nutlin-3.
Shin JS, Ha JH, He F, Muto Y, Ryu KS, Yoon HS, Kang S, Park SG, Park BC, Choi SU, Chi SW. Shin JS, et al. Biochem Biophys Res Commun. 2012 Mar 30;420(1):48-53. doi: 10.1016/j.bbrc.2012.02.113. Epub 2012 Feb 28. Biochem Biophys Res Commun. 2012. PMID: 22402281
1,194 results