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Nuclear enrichment of folate cofactors and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) protect de novo thymidylate biosynthesis during folate deficiency.
J Biol Chem. 2014 Oct 24;289(43):29642-50. doi: 10.1074/jbc.M114.599589. Epub 2014 Sep 11.
J Biol Chem. 2014.
PMID: 25213861
Free PMC article.
Arsenic trioxide targets MTHFD1 and SUMO-dependent nuclear de novo thymidylate biosynthesis.
Kamynina E, Lachenauer ER, DiRisio AC, Liebenthal RP, Field MS, Stover PJ.
Kamynina E, et al. Among authors: liebenthal rp.
Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2319-E2326. doi: 10.1073/pnas.1619745114. Epub 2017 Mar 6.
Proc Natl Acad Sci U S A. 2017.
PMID: 28265077
Free PMC article.
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