Xu L - Search Results

1

The intracellular Ca²⁺ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy.

Cheng X, Zhang X, Gao Q, Ali Samie M, Azar M, Tsang WL, Dong L, Sahoo N, Li X, Zhuo Y, Garrity AG, Wang X, Ferrer M, Dowling J, Xu L, Han R, Xu H. Cheng X, et al. Among authors: xu l, xu h. Nat Med. 2014 Oct;20(10):1187-92. doi: 10.1038/nm.3611. Epub 2014 Sep 14. Nat Med. 2014. PMID: 25216637 Free PMC article.

2

Equal force recovery in dysferlin-deficient and wild-type muscles following saponin exposure.

Zhao P, Xu L, Ait-Mou Y, de Tombe PP, Han R. Zhao P, et al. Among authors: xu l. J Biomed Biotechnol. 2011;2011:235216. doi: 10.1155/2011/235216. Epub 2011 Sep 18. J Biomed Biotechnol. 2011. PMID: 21941430 Free PMC article.

3

Dysferlin forms a dimer mediated by the C2 domains and the transmembrane domain in vitro and in living cells.

Xu L, Pallikkuth S, Hou Z, Mignery GA, Robia SL, Han R. Xu L, et al. PLoS One. 2011;6(11):e27884. doi: 10.1371/journal.pone.0027884. Epub 2011 Nov 14. PLoS One. 2011. PMID: 22110769 Free PMC article.

4

Targeted Myostatin Gene Editing in Multiple Mammalian Species Directed by a Single Pair of TALE Nucleases.

Xu L, Zhao P, Mariano A, Han R. Xu L, et al. Mol Ther Nucleic Acids. 2013 Jul 30;2(7):e112. doi: 10.1038/mtna.2013.39. Mol Ther Nucleic Acids. 2013. PMID: 23900226 Free PMC article.

5

Anoctamin 6 regulates C2C12 myoblast proliferation.

Zhao P, Torcaso A, Mariano A, Xu L, Mohsin S, Zhao L, Han R. Zhao P, et al. Among authors: xu l. PLoS One. 2014 Mar 24;9(3):e92749. doi: 10.1371/journal.pone.0092749. eCollection 2014. PLoS One. 2014. PMID: 24663380 Free PMC article.

6

CRISPR-mediated Genome Editing Restores Dystrophin Expression and Function in mdx Mice.

Xu L, Park KH, Zhao L, Xu J, El Refaey M, Gao Y, Zhu H, Ma J, Han R. Xu L, et al. Among authors: xu j. Mol Ther. 2016 Mar;24(3):564-9. doi: 10.1038/mt.2015.192. Epub 2015 Oct 9. Mol Ther. 2016. PMID: 26449883 Free PMC article.

7

Adeno-Associated Virus-Mediated Delivery of CRISPR for Cardiac Gene Editing in Mice.

Xu L, Gao Y, Lau YS, Han R. Xu L, et al. J Vis Exp. 2018 Aug 2;(138):57560. doi: 10.3791/57560. J Vis Exp. 2018. PMID: 30124643 Free PMC article.

8

Automated muscle histopathology analysis using CellProfiler.

Lau YS, Xu L, Gao Y, Han R. Lau YS, et al. Among authors: xu l. Skelet Muscle. 2018 Oct 18;8(1):32. doi: 10.1186/s13395-018-0178-6. Skelet Muscle. 2018. PMID: 30336774 Free PMC article.

9

Life-Long AAV-Mediated CRISPR Genome Editing in Dystrophic Heart Improves Cardiomyopathy without Causing Serious Lesions in mdx Mice.

Xu L, Lau YS, Gao Y, Li H, Han R. Xu L, et al. Mol Ther. 2019 Aug 7;27(8):1407-1414. doi: 10.1016/j.ymthe.2019.05.001. Epub 2019 May 15. Mol Ther. 2019. PMID: 31129119 Free PMC article.

10

Efficient precise in vivo base editing in adult dystrophic mice.

Xu L, Zhang C, Li H, Wang P, Gao Y, Mokadam NA, Ma J, Arnold WD, Han R. Xu L, et al. Nat Commun. 2021 Jun 17;12(1):3719. doi: 10.1038/s41467-021-23996-y. Nat Commun. 2021. PMID: 34140489 Free PMC article.

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