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Genetic heterogeneity in Alzheimer disease and implications for treatment strategies.
Ringman JM, Goate A, Masters CL, Cairns NJ, Danek A, Graff-Radford N, Ghetti B, Morris JC; Dominantly Inherited Alzheimer Network. Ringman JM, et al. Among authors: morris jc. Curr Neurol Neurosci Rep. 2014 Nov;14(11):499. doi: 10.1007/s11910-014-0499-8. Curr Neurol Neurosci Rep. 2014. PMID: 25217249 Free PMC article. Review.
HDDD2 is a familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions caused by a missense mutation in the signal peptide of progranulin.
Mukherjee O, Pastor P, Cairns NJ, Chakraverty S, Kauwe JS, Shears S, Behrens MI, Budde J, Hinrichs AL, Norton J, Levitch D, Taylor-Reinwald L, Gitcho M, Tu PH, Tenenholz Grinberg L, Liscic RM, Armendariz J, Morris JC, Goate AM. Mukherjee O, et al. Among authors: morris jc. Ann Neurol. 2006 Sep;60(3):314-22. doi: 10.1002/ana.20963. Ann Neurol. 2006. PMID: 16983685 Free PMC article.
Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants.
Grupe A, Abraham R, Li Y, Rowland C, Hollingworth P, Morgan A, Jehu L, Segurado R, Stone D, Schadt E, Karnoub M, Nowotny P, Tacey K, Catanese J, Sninsky J, Brayne C, Rubinsztein D, Gill M, Lawlor B, Lovestone S, Holmans P, O'Donovan M, Morris JC, Thal L, Goate A, Owen MJ, Williams J. Grupe A, et al. Among authors: morris jc. Hum Mol Genet. 2007 Apr 15;16(8):865-73. doi: 10.1093/hmg/ddm031. Epub 2007 Feb 22. Hum Mol Genet. 2007. PMID: 17317784
Neuropathologic heterogeneity in HDDD1: a familial frontotemporal lobar degeneration with ubiquitin-positive inclusions and progranulin mutation.
Behrens MI, Mukherjee O, Tu PH, Liscic RM, Grinberg LT, Carter D, Paulsmeyer K, Taylor-Reinwald L, Gitcho M, Norton JB, Chakraverty S, Goate AM, Morris JC, Cairns NJ. Behrens MI, et al. Among authors: morris jc. Alzheimer Dis Assoc Disord. 2007 Jan-Mar;21(1):1-7. doi: 10.1097/WAD.0b013e31803083f2. Alzheimer Dis Assoc Disord. 2007. PMID: 17334266
1,702 results