Yu ZH - Search Results

1

Protein tyrosine phosphatases as potential therapeutic targets.

He RJ, Yu ZH, Zhang RY, Zhang ZY. He RJ, et al. Among authors: yu zh. Acta Pharmacol Sin. 2014 Oct;35(10):1227-46. doi: 10.1038/aps.2014.80. Epub 2014 Sep 15. Acta Pharmacol Sin. 2014. PMID: 25220640 Free PMC article. Review.

2

Small molecule inhibitors of SHP2 tyrosine phosphatase discovered by virtual screening.

Yu ZH, Chen L, Wu L, Liu S, Wang L, Zhang ZY. Yu ZH, et al. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4238-42. doi: 10.1016/j.bmcl.2011.05.078. Epub 2011 May 30. Bioorg Med Chem Lett. 2011. PMID: 21669525 Free PMC article.

3

Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitors.

He Y, Zeng LF, Yu ZH, He R, Liu S, Zhang ZY. He Y, et al. Among authors: yu zh. Bioorg Med Chem. 2012 Mar 15;20(6):1940-6. doi: 10.1016/j.bmc.2011.11.004. Epub 2011 Nov 9. Bioorg Med Chem. 2012. PMID: 22133902 Free PMC article.

4

A highly selective and potent PTP-MEG2 inhibitor with therapeutic potential for type 2 diabetes.

Zhang S, Liu S, Tao R, Wei D, Chen L, Shen W, Yu ZH, Wang L, Jones DR, Dong XC, Zhang ZY. Zhang S, et al. Among authors: yu zh. J Am Chem Soc. 2012 Oct 31;134(43):18116-24. doi: 10.1021/ja308212y. Epub 2012 Oct 17. J Am Chem Soc. 2012. PMID: 23075115 Free PMC article.

5

Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.

He Y, Xu J, Yu ZH, Gunawan AM, Wu L, Wang L, Zhang ZY. He Y, et al. Among authors: yu zh. J Med Chem. 2013 Feb 14;56(3):832-42. doi: 10.1021/jm301781p. Epub 2013 Jan 25. J Med Chem. 2013. PMID: 23305444 Free PMC article.

6

Therapeutic potential of targeting the oncogenic SHP2 phosphatase.

Zeng LF, Zhang RY, Yu ZH, Li S, Wu L, Gunawan AM, Lane BS, Mali RS, Li X, Chan RJ, Kapur R, Wells CD, Zhang ZY. Zeng LF, et al. Among authors: yu zh. J Med Chem. 2014 Aug 14;57(15):6594-609. doi: 10.1021/jm5006176. Epub 2014 Jul 28. J Med Chem. 2014. PMID: 25003231 Free PMC article.

7

Novel Anticancer Agents Based on Targeting the Trimer Interface of the PRL Phosphatase.

Bai Y, Yu ZH, Liu S, Zhang L, Zhang RY, Zeng LF, Zhang S, Zhang ZY. Bai Y, et al. Among authors: yu zh. Cancer Res. 2016 Aug 15;76(16):4805-15. doi: 10.1158/0008-5472.CAN-15-2323. Epub 2016 Jun 20. Cancer Res. 2016. PMID: 27325652 Free PMC article.

8

Discovery and Evaluation of PRL Trimer Disruptors for Novel Anticancer Agents.

Bai Y, Yu ZH, Zhang ZY. Bai Y, et al. Among authors: yu zh. Methods Mol Biol. 2016;1447:121-38. doi: 10.1007/978-1-4939-3746-2_8. Methods Mol Biol. 2016. PMID: 27514804

9

SHP2 phosphatase as a novel therapeutic target for melanoma treatment.

Zhang RY, Yu ZH, Zeng L, Zhang S, Bai Y, Miao J, Chen L, Xie J, Zhang ZY. Zhang RY, et al. Among authors: yu zh. Oncotarget. 2016 Nov 8;7(45):73817-73829. doi: 10.18632/oncotarget.12074. Oncotarget. 2016. PMID: 27650545 Free PMC article.

10

Regulatory Mechanisms and Novel Therapeutic Targeting Strategies for Protein Tyrosine Phosphatases.

Yu ZH, Zhang ZY. Yu ZH, et al. Chem Rev. 2018 Feb 14;118(3):1069-1091. doi: 10.1021/acs.chemrev.7b00105. Epub 2017 May 25. Chem Rev. 2018. PMID: 28541680 Free PMC article. Review.

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