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An exploratory double-blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with Huntington's disease.
Süssmuth SD, Haider S, Landwehrmeyer GB, Farmer R, Frost C, Tripepi G, Andersen CA, Di Bacco M, Lamanna C, Diodato E, Massai L, Diamanti D, Mori E, Magnoni L, Dreyhaupt J, Schiefele K, Craufurd D, Saft C, Rudzinska M, Ryglewicz D, Orth M, Brzozy S, Baran A, Pollio G, Andre R, Tabrizi SJ, Darpo B, Westerberg G; PADDINGTON Consortium. Süssmuth SD, et al. Among authors: schiefele k. Br J Clin Pharmacol. 2015 Mar;79(3):465-76. doi: 10.1111/bcp.12512. Br J Clin Pharmacol. 2015. PMID: 25223731 Free PMC article. Clinical Trial.