Pos KM - Search Results

1

Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB.

Eicher T, Seeger MA, Anselmi C, Zhou W, Brandstätter L, Verrey F, Diederichs K, Faraldo-Gómez JD, Pos KM. Eicher T, et al. Among authors: pos km. Elife. 2014 Sep 19;3:e03145. doi: 10.7554/eLife.03145. Elife. 2014. PMID: 25248080 Free PMC article.

2

Purification, crystallization and preliminary diffraction studies of AcrB, an inner-membrane multi-drug efflux protein.

Pos KM, Diederichs K. Pos KM, et al. Acta Crystallogr D Biol Crystallogr. 2002 Oct;58(Pt 10 Pt 2):1865-7. doi: 10.1107/s0907444902013963. Epub 2002 Sep 28. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12351840

3

Crystallographic analysis of AcrB.

Pos KM, Schiefner A, Seeger MA, Diederichs K. Pos KM, et al. FEBS Lett. 2004 Apr 30;564(3):333-9. doi: 10.1016/S0014-5793(04)00272-8. FEBS Lett. 2004. PMID: 15111118 Free article.

4

Basolateral aromatic amino acid transporter TAT1 (Slc16a10) functions as an efflux pathway.

Ramadan T, Camargo SM, Summa V, Hunziker P, Chesnov S, Pos KM, Verrey F. Ramadan T, et al. Among authors: pos km. J Cell Physiol. 2006 Mar;206(3):771-9. doi: 10.1002/jcp.20531. J Cell Physiol. 2006. PMID: 16245314

5

Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism.

Seeger MA, Schiefner A, Eicher T, Verrey F, Diederichs K, Pos KM. Seeger MA, et al. Among authors: pos km. Science. 2006 Sep 1;313(5791):1295-8. doi: 10.1126/science.1131542. Science. 2006. PMID: 16946072

6

Functional characterization of a NapA Na(+)/H(+) antiporter from Thermus thermophilus.

Furrer EM, Ronchetti MF, Verrey F, Pos KM. Furrer EM, et al. Among authors: pos km. FEBS Lett. 2007 Feb 6;581(3):572-8. doi: 10.1016/j.febslet.2006.12.059. Epub 2007 Jan 17. FEBS Lett. 2007. PMID: 17254570 Free article.

7

Recycling of aromatic amino acids via TAT1 allows efflux of neutral amino acids via LAT2-4F2hc exchanger.

Ramadan T, Camargo SM, Herzog B, Bordin M, Pos KM, Verrey F. Ramadan T, et al. Among authors: pos km. Pflugers Arch. 2007 Jun;454(3):507-16. doi: 10.1007/s00424-007-0209-3. Epub 2007 Feb 2. Pflugers Arch. 2007. PMID: 17273864

8

Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB.

Seeger MA, von Ballmoos C, Eicher T, Brandstätter L, Verrey F, Diederichs K, Pos KM. Seeger MA, et al. Among authors: pos km. Nat Struct Mol Biol. 2008 Feb;15(2):199-205. doi: 10.1038/nsmb.1379. Epub 2008 Jan 27. Nat Struct Mol Biol. 2008. PMID: 18223659

9

The AcrB efflux pump: conformational cycling and peristalsis lead to multidrug resistance.

Seeger MA, Diederichs K, Eicher T, Brandstätter L, Schiefner A, Verrey F, Pos KM. Seeger MA, et al. Among authors: pos km. Curr Drug Targets. 2008 Sep;9(9):729-49. doi: 10.2174/138945008785747789. Curr Drug Targets. 2008. PMID: 18781920 Review.

10

Site-directed mutagenesis reveals putative substrate binding residues in the Escherichia coli RND efflux pump AcrB.

Bohnert JA, Schuster S, Seeger MA, Fähnrich E, Pos KM, Kern WV. Bohnert JA, et al. Among authors: pos km. J Bacteriol. 2008 Dec;190(24):8225-9. doi: 10.1128/JB.00912-08. Epub 2008 Oct 10. J Bacteriol. 2008. PMID: 18849422 Free PMC article.

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