Zhang Q - Search Results

1

Synthesis and evaluation of benzimidazole carbamates bearing indole moieties for antiproliferative and antitubulin activities.

Guan Q, Han C, Zuo D, Zhai M, Li Z, Zhang Q, Zhai Y, Jiang X, Bao K, Wu Y, Zhang W. Guan Q, et al. Among authors: zhang q, zhang w. Eur J Med Chem. 2014 Nov 24;87:306-15. doi: 10.1016/j.ejmech.2014.09.071. Epub 2014 Sep 28. Eur J Med Chem. 2014. PMID: 25262051

2

3-(3,4,5-Trimethoxyphenylselenyl)-1H-indoles and their selenoxides as combretastatin A-4 analogs: microwave-assisted synthesis and biological evaluation.

Wen Z, Xu J, Wang Z, Qi H, Xu Q, Bai Z, Zhang Q, Bao K, Wu Y, Zhang W. Wen Z, et al. Among authors: zhang q, zhang w. Eur J Med Chem. 2015 Jan 27;90:184-94. doi: 10.1016/j.ejmech.2014.11.024. Epub 2014 Nov 13. Eur J Med Chem. 2015. PMID: 25461319

3

Design, synthesis and antitumor activity of novel thiophene-pyrimidine derivatives as EGFR inhibitors overcoming T790M and L858R/T790M mutations.

Xiao Z, Zhou Z, Chu C, Zhang Q, Zhou L, Yang Z, Li X, Yu L, Zheng P, Xu S, Zhu W. Xiao Z, et al. Among authors: zhang q. Eur J Med Chem. 2020 Oct 1;203:112511. doi: 10.1016/j.ejmech.2020.112511. Epub 2020 Jul 6. Eur J Med Chem. 2020. PMID: 32679450

4

Fluoroalkane thioheterocyclic derivatives and their antitumor activity.

Li G, Sun Q, Wang D, Xu Y, Zhuang J, Zhang Q, Sun D. Li G, et al. Among authors: zhang q. Eur J Med Chem. 2015 Mar 26;93:423-30. doi: 10.1016/j.ejmech.2015.02.031. Epub 2015 Feb 20. Eur J Med Chem. 2015. PMID: 25728023

5

Design, synthesis, docking, molecular dynamics and bioevaluation studies on novel N-methylpicolinamide and thienopyrimidine derivatives with inhibiting NF-κB and TAK1 activities: Cheminformatics tools RDKit applied in drug design.

Wang L, Zhang Q, Wang Z, Zhu W, Tan N. Wang L, et al. Among authors: zhang q. Eur J Med Chem. 2021 Nov 5;223:113576. doi: 10.1016/j.ejmech.2021.113576. Epub 2021 Jun 5. Eur J Med Chem. 2021. PMID: 34153577

6

Design, synthesis and biological evaluation of 4-(pyridin-4-yloxy)benzamide derivatives bearing a 5-methylpyridazin-3(2H)-one fragment.

Xiong H, Zhang J, Zhang Q, Duan Y, Zhang H, Zheng P, Tang Q. Xiong H, et al. Among authors: zhang q, zhang j, zhang h. Bioorg Med Chem Lett. 2020 May 1;30(9):127076. doi: 10.1016/j.bmcl.2020.127076. Epub 2020 Mar 4. Bioorg Med Chem Lett. 2020. PMID: 32173195

7

Discovery of thiapyran-pyrimidine derivatives as potential EGFR inhibitors.

Xiao Z, Chu C, Zhou L, Zhou Z, Zhang Q, Yang F, Yang Z, Zheng P, Xu S, Zhu W. Xiao Z, et al. Among authors: zhang q. Bioorg Med Chem. 2020 Oct 1;28(19):115669. doi: 10.1016/j.bmc.2020.115669. Epub 2020 Jul 28. Bioorg Med Chem. 2020. PMID: 32912435

8

Synthesis and evaluation of FAK inhibitors with a 5-fluoro-7H-pyrrolo[2,3-d]pyrimidine scaffold as anti-hepatocellular carcinoma agents.

Tan H, Liu Y, Gong C, Zhang J, Huang J, Zhang Q. Tan H, et al. Among authors: zhang q, zhang j. Eur J Med Chem. 2021 Nov 5;223:113670. doi: 10.1016/j.ejmech.2021.113670. Epub 2021 Jun 25. Eur J Med Chem. 2021. PMID: 34214842

9

Synthesis and cytotoxic studies of novel 5-phenylisatin derivatives and their anti-migration and anti-angiogenic evaluation.

Zhang Q, Teng Y, Yuan Y, Ruan T, Wang Q, Gao X, Zhou Y, Han K, Yu P, Lu K. Zhang Q, et al. Eur J Med Chem. 2018 Aug 5;156:800-814. doi: 10.1016/j.ejmech.2018.07.032. Epub 2018 Jul 25. Eur J Med Chem. 2018. PMID: 30055465 Free PMC article.

10

Design, synthesis, and evaluation of novel Akt1 inhibitors based on an indole scaffold.

Yang D, Tong D, Zhang Q, Wang Y, Sun J, Zhang F, Zhao G. Yang D, et al. Among authors: zhang q, zhang f. Chem Biol Drug Des. 2017 Nov;90(5):791-803. doi: 10.1111/cbdd.13000. Epub 2017 May 7. Chem Biol Drug Des. 2017. PMID: 28390089

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