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A large candidate-gene association study suggests genetic variants at IRF5 and PRDM1 to be associated with aggressive periodontitis.
Schaefer AS, Jochens A, Dommisch H, Graetz C, Jockel-Schneider Y, Harks I, Staufenbiel I, Meyle J, Eickholz P, Folwaczny M, Laine M, Noack B, Wijmenga C, Lieb W, Bruckmann C, Schreiber S, Jepsen S, Loos BG. Schaefer AS, et al. Among authors: laine m. J Clin Periodontol. 2014 Dec;41(12):1122-31. doi: 10.1111/jcpe.12314. Epub 2014 Nov 15. J Clin Periodontol. 2014. PMID: 25263394
Genetic susceptibility to periodontitis.
Laine ML, Crielaard W, Loos BG. Laine ML, et al. Periodontol 2000. 2012 Feb;58(1):37-68. doi: 10.1111/j.1600-0757.2011.00415.x. Periodontol 2000. 2012. PMID: 22133366 Review. No abstract available.
Common genetic risk variants of TLR2 are not associated with periodontitis in large European case-control populations.
Richter GM, Graetz C, Pohler P, Nothnagel M, Dommisch H, Laine ML, Folwaczny M, Noack B, Eickholz P, Groessner-Schreiber B, Jepsen S, Loos BG, Schreiber S, Schaefer AS. Richter GM, et al. Among authors: laine ml. J Clin Periodontol. 2012 Apr;39(4):315-22. doi: 10.1111/j.1600-051X.2011.01846.x. Epub 2012 Jan 18. J Clin Periodontol. 2012. PMID: 22251071
A 3' UTR transition within DEFB1 is associated with chronic and aggressive periodontitis.
Schaefer AS, Richter GM, Nothnagel M, Laine ML, Rühling A, Schäfer C, Cordes N, Noack B, Folwaczny M, Glas J, Dörfer C, Dommisch H, Groessner-Schreiber B, Jepsen S, Loos BG, Schreiber S. Schaefer AS, et al. Among authors: laine ml. Genes Immun. 2010 Jan;11(1):45-54. doi: 10.1038/gene.2009.75. Epub 2009 Oct 15. Genes Immun. 2010. PMID: 19829306
COX-2 is associated with periodontitis in Europeans.
Schaefer AS, Richter GM, Nothnagel M, Laine ML, Noack B, Glas J, Schrezenmeir J, Groessner-Schreiber B, Jepsen S, Loos BG, Schreiber S. Schaefer AS, et al. Among authors: laine ml. J Dent Res. 2010 Apr;89(4):384-8. doi: 10.1177/0022034509359575. Epub 2010 Feb 22. J Dent Res. 2010. PMID: 20177132
What is the Contribution of Genetics to Periodontal Risk?
Loos BG, Papantonopoulos G, Jepsen S, Laine ML. Loos BG, et al. Dent Clin North Am. 2015 Oct;59(4):761-80. doi: 10.1016/j.cden.2015.06.005. Epub 2015 Aug 1. Dent Clin North Am. 2015. PMID: 26427567 Review.
940 results