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HIV acquisition is associated with increased antimicrobial peptides and reduced HIV neutralizing IgA in the foreskin prepuce of uncircumcised men.
Hirbod T, Kong X, Kigozi G, Ndyanabo A, Serwadda D, Prodger JL, Tobian AA, Nalugoda F, Wawer MJ, Shahabi K, Rojas OL, Gommerman JL, Broliden K, Kaul R, Gray RH. Hirbod T, et al. Among authors: gommerman jl. PLoS Pathog. 2014 Oct 2;10(10):e1004416. doi: 10.1371/journal.ppat.1004416. eCollection 2014 Oct. PLoS Pathog. 2014. PMID: 25275513 Free PMC article. Clinical Trial.
B cell depletion with anti-CD20 promotes neuroprotection in a BAFF-dependent manner in mice and humans.
Wang AA, Luessi F, Neziraj T, Pössnecker E, Zuo M, Engel S, Hanuscheck N, Florescu A, Bugbee E, Ma XI, Rana F, Lee D, Ward LA, Kuhle J, Himbert J, Schraad M, van Puijenbroek E, Klein C, Urich E, Ramaglia V, Pröbstel AK, Zipp F, Gommerman JL. Wang AA, et al. Among authors: gommerman jl. Sci Transl Med. 2024 Mar 6;16(737):eadi0295. doi: 10.1126/scitranslmed.adi0295. Epub 2024 Mar 6. Sci Transl Med. 2024. PMID: 38446903
The protozoan commensal Tritrichomonas musculis is a natural adjuvant for mucosal IgA.
Cao EY, Burrows K, Chiaranunt P, Popovic A, Zhou X, Xie C, Thakur A, Britton G, Spindler M, Ngai L, Tai SL, Dasoveanu DC, Nguyen A, Faith JJ, Parkinson J, Gommerman JL, Mortha A. Cao EY, et al. Among authors: gommerman jl. J Exp Med. 2024 Dec 2;221(12):e20221727. doi: 10.1084/jem.20221727. Epub 2024 Nov 13. J Exp Med. 2024. PMID: 39535524 Free PMC article.
Astrocytes ACLYmate to chronic neuroinflammation.
Champagne-Jorgensen K, Gommerman J. Champagne-Jorgensen K, et al. Trends Immunol. 2024 May;45(5):320-321. doi: 10.1016/j.it.2024.04.003. Epub 2024 Apr 16. Trends Immunol. 2024. PMID: 38632002 Review.
Editorial: Environmental factors in autoimmunity.
Dunn SE, Correale J, Gommerman JL, Horwitz MS. Dunn SE, et al. Among authors: gommerman jl. Front Immunol. 2024 Jan 16;14:1361884. doi: 10.3389/fimmu.2023.1361884. eCollection 2023. Front Immunol. 2024. PMID: 38292480 Free PMC article. No abstract available.
Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control.
Swanson RV, Gupta A, Foreman TW, Lu L, Choreno-Parra JA, Mbandi SK, Rosa BA, Akter S, Das S, Ahmed M, Garcia-Hernandez ML, Singh DK, Esaulova E, Artyomov MN, Gommerman J, Mehra S, Zuniga J, Mitreva M, Scriba TJ, Rangel-Moreno J, Kaushal D, Khader SA. Swanson RV, et al. Nat Immunol. 2023 May;24(5):855-868. doi: 10.1038/s41590-023-01476-3. Epub 2023 Apr 3. Nat Immunol. 2023. PMID: 37012543 Free PMC article.
Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut.
Fritz JH, Rojas OL, Simard N, McCarthy DD, Hapfelmeier S, Rubino S, Robertson SJ, Larijani M, Gosselin J, Ivanov II, Martin A, Casellas R, Philpott DJ, Girardin SE, McCoy KD, Macpherson AJ, Paige CJ, Gommerman JL. Fritz JH, et al. Among authors: gommerman jl. Nature. 2011 Dec 11;481(7380):199-203. doi: 10.1038/nature10698. Nature. 2011. PMID: 22158124 Free PMC article.
129 results