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Suppression of deacetylase SIRT1 mediates tumor-suppressive NOTCH response and offers a novel treatment option in metastatic Ewing sarcoma.
Ban J, Aryee DN, Fourtouna A, van der Ent W, Kauer M, Niedan S, Machado I, Rodriguez-Galindo C, Tirado OM, Schwentner R, Picci P, Flanagan AM, Berg V, Strauss SJ, Scotlandi K, Lawlor ER, Snaar-Jagalska E, Llombart-Bosch A, Kovar H. Ban J, et al. Among authors: kovar h. Cancer Res. 2014 Nov 15;74(22):6578-88. doi: 10.1158/0008-5472.CAN-14-1736. Epub 2014 Oct 3. Cancer Res. 2014. PMID: 25281719
MIC2 is a specific marker for Ewing's sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of Ewing's sarcoma and peripheral primitive neuroectodermal tumors from MIC2 expression and specific chromosome aberration.
Ambros IM, Ambros PF, Strehl S, Kovar H, Gadner H, Salzer-Kuntschik M. Ambros IM, et al. Among authors: kovar h. Cancer. 1991 Apr 1;67(7):1886-93. doi: 10.1002/1097-0142(19910401)67:7<1886::aid-cncr2820670712>3.0.co;2-u. Cancer. 1991. PMID: 1848471
[The EWS gene rearrangement in Ewing tumors: key to the disease].
Kovar H, Zoubek A, Pfleiderer C, Jug G, Auinger A, Aryee D, Ambros PF, Salzer-Kuntschik M, Amann G, Windhager R, et al. Kovar H, et al. Klin Padiatr. 1994 Jul-Aug;206(4):196-200. doi: 10.1055/s-2008-1046605. Klin Padiatr. 1994. PMID: 7967416 German.
140 results