Mlinarič-Raščan I - Search Results

1

From pharmacogenetics to pharmacometabolomics: SAM modulates TPMT activity.

Karas-Kuželički N, Šmid A, Tamm R, Metspalu A, Mlinarič-Raščan I. Karas-Kuželički N, et al. Pharmacogenomics. 2014 Aug;15(11):1437-49. doi: 10.2217/pgs.14.84. Pharmacogenomics. 2014. PMID: 25303295 Free article.

2

Thiopurine S-methyltransferase pharmacogenetics: genotype to phenotype correlation in the Slovenian population.

Milek M, Murn J, Jaksic Z, Lukac Bajalo J, Jazbec J, Mlinaric Rascan I. Milek M, et al. Pharmacology. 2006;77(3):105-14. doi: 10.1159/000093278. Epub 2006 May 10. Pharmacology. 2006. PMID: 16691038

3

Heterozygosity at the TPMT gene locus, augmented by mutated MTHFR gene, predisposes to 6-MP related toxicities in childhood ALL patients.

Karas-Kuzelicki N, Jazbec J, Milek M, Mlinaric-Rascan I. Karas-Kuzelicki N, et al. Leukemia. 2009 May;23(5):971-4. doi: 10.1038/leu.2008.317. Epub 2008 Nov 6. Leukemia. 2009. PMID: 18987660 No abstract available.

4

5,10-Methylenetetrahydrofolate reductase (MTHFR) low activity genotypes reduce the risk of relapse-related acute lymphoblastic leukemia (ALL).

Karas Kuzelicki N, Milek M, Jazbec J, Mlinaric-Rascan I. Karas Kuzelicki N, et al. Leuk Res. 2009 Oct;33(10):1344-8. doi: 10.1016/j.leukres.2008.12.011. Leuk Res. 2009. PMID: 19178944

5

S-adenosylmethionine regulates thiopurine methyltransferase activity and decreases 6-mercaptopurine cytotoxicity in MOLT lymphoblasts.

Milek M, Karas Kuzelicki N, Smid A, Mlinaric-Rascan I. Milek M, et al. Biochem Pharmacol. 2009 Jun 15;77(12):1845-53. doi: 10.1016/j.bcp.2009.03.006. Epub 2009 Mar 19. Biochem Pharmacol. 2009. PMID: 19428339

6

Individualization of thiopurine therapy: thiopurine S-methyltransferase and beyond.

Karas-Kuzelicki N, Mlinaric-Rascan I. Karas-Kuzelicki N, et al. Pharmacogenomics. 2009 Aug;10(8):1309-22. doi: 10.2217/pgs.09.78. Pharmacogenomics. 2009. PMID: 19663675 Review.

7

MTHFR and TYMS genotypes influence TPMT activity and its differential modulation in males and females.

Karas-Kuzelicki N, Milek M, Mlinaric-Rascan I. Karas-Kuzelicki N, et al. Clin Biochem. 2010 Jan;43(1-2):37-42. doi: 10.1016/j.clinbiochem.2009.09.003. Epub 2009 Sep 11. Clin Biochem. 2010. PMID: 19748501

8

Influence of the polymorphism in candidate genes on late cardiac damage in patients treated due to acute leukemia in childhood.

Rajić V, Aplenc R, Debeljak M, Prestor VV, Karas-Kuzelicki N, Mlinaric-Rascan I, Jazbec J. Rajić V, et al. Leuk Lymphoma. 2009 Oct;50(10):1693-8. doi: 10.1080/10428190903177212. Leuk Lymphoma. 2009. PMID: 19863340

9

Post-translational stabilization of thiopurine S-methyltransferase by S-adenosyl-L-methionine reveals regulation of TPMT*1 and *3C allozymes.

Milek M, Smid A, Tamm R, Kuzelicki NK, Metspalu A, Mlinaric-Rascan I. Milek M, et al. Biochem Pharmacol. 2012 Apr 1;83(7):969-76. doi: 10.1016/j.bcp.2012.01.010. Epub 2012 Jan 17. Biochem Pharmacol. 2012. PMID: 22274639

10

Association of ITPA genotype with event-free survival and relapse rates in children with acute lymphoblastic leukemia undergoing maintenance therapy.

Smid A, Karas-Kuzelicki N, Milek M, Jazbec J, Mlinaric-Rascan I. Smid A, et al. PLoS One. 2014 Oct 10;9(10):e109551. doi: 10.1371/journal.pone.0109551. eCollection 2014. PLoS One. 2014. PMID: 25303517 Free PMC article.

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