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Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance.
Grünberg JR, Hoffmann JM, Hedjazifar S, Nerstedt A, Jenndahl L, Elvin J, Castellot J, Wei L, Movérare-Skrtic S, Ohlsson C, Holm LM, Bäckhed F, Syed I, Bosch F, Saghatelian A, Kahn BB, Hammarstedt A, Smith U. Grünberg JR, et al. Among authors: hammarstedt a. Sci Rep. 2017 Feb 27;7:43515. doi: 10.1038/srep43515. Sci Rep. 2017. PMID: 28240264 Free PMC article.
Retinol-binding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines in macrophages through a c-Jun N-terminal kinase- and toll-like receptor 4-dependent and retinol-independent mechanism.
Norseen J, Hosooka T, Hammarstedt A, Yore MM, Kant S, Aryal P, Kiernan UA, Phillips DA, Maruyama H, Kraus BJ, Usheva A, Davis RJ, Smith U, Kahn BB. Norseen J, et al. Among authors: hammarstedt a. Mol Cell Biol. 2012 May;32(10):2010-9. doi: 10.1128/MCB.06193-11. Epub 2012 Mar 19. Mol Cell Biol. 2012. PMID: 22431523 Free PMC article.
Insulin resistance and impaired adipogenesis.
Gustafson B, Hedjazifar S, Gogg S, Hammarstedt A, Smith U. Gustafson B, et al. Among authors: hammarstedt a. Trends Endocrinol Metab. 2015 Apr;26(4):193-200. doi: 10.1016/j.tem.2015.01.006. Epub 2015 Feb 18. Trends Endocrinol Metab. 2015. PMID: 25703677 Review.
70 results