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Therapeutic opportunities for targeting cold pain pathways.
Yin K, Zimmermann K, Vetter I, Lewis RJ. Yin K, et al. Among authors: zimmermann k. Biochem Pharmacol. 2015 Jan 15;93(2):125-40. doi: 10.1016/j.bcp.2014.09.024. Epub 2014 Oct 12. Biochem Pharmacol. 2015. PMID: 25316567 Free article. Review.
Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling.
Vetter I, Touska F, Hess A, Hinsbey R, Sattler S, Lampert A, Sergejeva M, Sharov A, Collins LS, Eberhardt M, Engel M, Cabot PJ, Wood JN, Vlachová V, Reeh PW, Lewis RJ, Zimmermann K. Vetter I, et al. Among authors: zimmermann k. EMBO J. 2012 Oct 3;31(19):3795-808. doi: 10.1038/emboj.2012.207. Epub 2012 Jul 31. EMBO J. 2012. PMID: 22850668 Free PMC article.
Analgesic treatment of ciguatoxin-induced cold allodynia.
Zimmermann K, Deuis JR, Inserra MC, Collins LS, Namer B, Cabot PJ, Reeh PW, Lewis RJ, Vetter I. Zimmermann K, et al. Pain. 2013 Oct;154(10):1999-2006. doi: 10.1016/j.pain.2013.06.015. Epub 2013 Jun 15. Pain. 2013. PMID: 23778293
Amplified cold transduction in native nociceptors by M-channel inhibition.
Vetter I, Hein A, Sattler S, Hessler S, Touska F, Bressan E, Parra A, Hager U, Leffler A, Boukalova S, Nissen M, Lewis RJ, Belmonte C, Alzheimer C, Huth T, Vlachova V, Reeh PW, Zimmermann K. Vetter I, et al. Among authors: zimmermann k. J Neurosci. 2013 Oct 16;33(42):16627-41. doi: 10.1523/JNEUROSCI.1473-13.2013. J Neurosci. 2013. PMID: 24133266 Free PMC article.
Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1.
Inserra MC, Israel MR, Caldwell A, Castro J, Deuis JR, Harrington AM, Keramidas A, Garcia-Caraballo S, Maddern J, Erickson A, Grundy L, Rychkov GY, Zimmermann K, Lewis RJ, Brierley SM, Vetter I. Inserra MC, et al. Among authors: zimmermann k. Sci Rep. 2017 Feb 22;7:42810. doi: 10.1038/srep42810. Sci Rep. 2017. PMID: 28225079 Free PMC article.
713 results