Zhu A - Search Results

1

Radiosynthesis and evaluation of an 18F-labeled positron emission tomography (PET) radioligand for metabotropic glutamate receptor subtype 4 (mGlu4).

Kil KE, Poutiainen P, Zhang Z, Zhu A, Choi JK, Jokivarsi K, Brownell AL. Kil KE, et al. Among authors: zhu a. J Med Chem. 2014 Nov 13;57(21):9130-8. doi: 10.1021/jm501245b. Epub 2014 Oct 27. J Med Chem. 2014. PMID: 25330258 Free PMC article.

2

Synthesis and preliminary biological evaluation of 3-[(18)F]fluoro-5-(2-pyridinylethynyl)benzonitrile as a PET radiotracer for imaging metabotropic glutamate receptor subtype 5.

Wang JQ, Tueckmantel W, Zhu A, Pellegrino D, Brownell AL. Wang JQ, et al. Among authors: zhu a. Synapse. 2007 Dec;61(12):951-61. doi: 10.1002/syn.20445. Synapse. 2007. PMID: 17787003

3

Development of [(123)I]IPEB and [(123)I]IMPEB as SPECT Radioligands for Metabotropic Glutamate Receptor Subtype 5.

Kil KE, Zhu A, Zhang Z, Choi JK, Kura S, Gong C, Brownell AL. Kil KE, et al. Among authors: zhu a. ACS Med Chem Lett. 2014 Apr 6;5(6):652-6. doi: 10.1021/ml500007z. eCollection 2014 Jun 12. ACS Med Chem Lett. 2014. PMID: 24944738 Free PMC article.

4

Functional modulation of G-protein coupled receptors during Parkinson disease-like neurodegeneration.

Jenkins BG, Zhu A, Poutiainen P, Choi JK, Kil KE, Zhang Z, Kuruppu D, Aytan N, Dedeoglu A, Brownell AL. Jenkins BG, et al. Among authors: zhu a. Neuropharmacology. 2016 Sep;108:462-73. doi: 10.1016/j.neuropharm.2015.11.010. Epub 2015 Nov 12. Neuropharmacology. 2016. PMID: 26581500 Free PMC article.

5

PET imaging studies show enhanced expression of mGluR5 and inflammatory response during progressive degeneration in ALS mouse model expressing SOD1-G93A gene.

Brownell AL, Kuruppu D, Kil KE, Jokivarsi K, Poutiainen P, Zhu A, Maxwell M. Brownell AL, et al. Among authors: zhu a. J Neuroinflammation. 2015 Nov 24;12:217. doi: 10.1186/s12974-015-0439-9. J Neuroinflammation. 2015. PMID: 26597638 Free PMC article.

6

Synthesis and evaluation of N-(methylthiophenyl)picolinamide derivatives as PET radioligands for metabotropic glutamate receptor subtype 4.

Kil KE, Poutiainen P, Zhang Z, Zhu A, Kuruppu D, Prabhakar S, Choi JK, Tannous BA, Brownell AL. Kil KE, et al. Among authors: zhu a. Bioorg Med Chem Lett. 2016 Jan 1;26(1):133-9. doi: 10.1016/j.bmcl.2015.11.015. Epub 2015 Nov 10. Bioorg Med Chem Lett. 2016. PMID: 26602273 Free PMC article.

7

Synthesis and Characterization of Fluorine-18-Labeled N-(4-Chloro-3-((fluoromethyl-d₂)thio)phenyl)picolinamide for Imaging of mGluR4 in Brain.

Wang J, Qu X, Shoup TM, Yuan G, Afshar S, Pan C, Zhu A, Choi JK, Kang HJ, Poutiainen P, El Fakhri G, Zhang Z, Brownell AL. Wang J, et al. Among authors: zhu a. J Med Chem. 2020 Mar 26;63(6):3381-3389. doi: 10.1021/acs.jmedchem.0c00201. Epub 2020 Mar 4. J Med Chem. 2020. PMID: 32081008 Free PMC article.

8

Methoxyphenylethynyl, methoxypyridylethynyl and phenylethynyl derivatives of pyridine: synthesis, radiolabeling and evaluation of new PET ligands for metabotropic glutamate subtype 5 receptors.

Yu M, Tueckmantel W, Wang X, Zhu A, Kozikowski AP, Brownell AL. Yu M, et al. Among authors: zhu a. Nucl Med Biol. 2005 Aug;32(6):631-40. doi: 10.1016/j.nucmedbio.2005.05.004. Nucl Med Biol. 2005. PMID: 16026710

9

Evaluation of four pyridine analogs to characterize 6-OHDA-induced modulation of mGluR5 function in rat brain using microPET studies.

Zhu A, Wang X, Yu M, Wang JQ, Brownell AL. Zhu A, et al. J Cereb Blood Flow Metab. 2007 Sep;27(9):1623-31. doi: 10.1038/sj.jcbfm.9600461. Epub 2007 Feb 14. J Cereb Blood Flow Metab. 2007. PMID: 17299451

10

Positron emission tomography of herpes simplex virus 1 oncolysis.

Kuruppu D, Brownell AL, Zhu A, Yu M, Wang X, Kulu Y, Fuchs BC, Kawasaki H, Tanabe KK. Kuruppu D, et al. Among authors: zhu a. Cancer Res. 2007 Apr 1;67(7):3295-300. doi: 10.1158/0008-5472.CAN-06-4062. Cancer Res. 2007. PMID: 17409438

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