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Page 1
Medical reversal of chronic sinusitis in a cystic fibrosis patient with ivacaftor.
Chang EH, Tang XX, Shah VS, Launspach JL, Ernst SE, Hilkin B, Karp PH, Abou Alaiwa MH, Graham SM, Hornick DB, Welsh MJ, Stoltz DA, Zabner J. Chang EH, et al. Among authors: shah vs. Int Forum Allergy Rhinol. 2015 Feb;5(2):178-81. doi: 10.1002/alr.21440. Epub 2014 Oct 31. Int Forum Allergy Rhinol. 2015. PMID: 25363320 Free PMC article.
Airway acidification initiates host defense abnormalities in cystic fibrosis mice.
Shah VS, Meyerholz DK, Tang XX, Reznikov L, Abou Alaiwa M, Ernst SE, Karp PH, Wohlford-Lenane CL, Heilmann KP, Leidinger MR, Allen PD, Zabner J, McCray PB Jr, Ostedgaard LS, Stoltz DA, Randak CO, Welsh MJ. Shah VS, et al. Science. 2016 Jan 29;351(6272):503-7. doi: 10.1126/science.aad5589. Science. 2016. PMID: 26823428 Free PMC article.
Lentiviral-mediated phenotypic correction of cystic fibrosis pigs.
Cooney AL, Abou Alaiwa MH, Shah VS, Bouzek DC, Stroik MR, Powers LS, Gansemer ND, Meyerholz DK, Welsh MJ, Stoltz DA, Sinn PL, McCray PB Jr. Cooney AL, et al. Among authors: shah vs. JCI Insight. 2016 Sep 8;1(14):e88730. doi: 10.1172/jci.insight.88730. JCI Insight. 2016. PMID: 27656681 Free PMC article.
CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypes.
Steines B, Dickey DD, Bergen J, Excoffon KJ, Weinstein JR, Li X, Yan Z, Abou Alaiwa MH, Shah VS, Bouzek DC, Powers LS, Gansemer ND, Ostedgaard LS, Engelhardt JF, Stoltz DA, Welsh MJ, Sinn PL, Schaffer DV, Zabner J. Steines B, et al. Among authors: shah vs. JCI Insight. 2016 Sep 8;1(14):e88728. doi: 10.1172/jci.insight.88728. JCI Insight. 2016. PMID: 27699238 Free PMC article.
Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function in Primary Human Airway Epithelia.
Dong Q, Ernst SE, Ostedgaard LS, Shah VS, Ver Heul AR, Welsh MJ, Randak CO. Dong Q, et al. Among authors: shah vs. J Biol Chem. 2015 May 29;290(22):14140-53. doi: 10.1074/jbc.M114.611616. Epub 2015 Apr 17. J Biol Chem. 2015. PMID: 25887396 Free PMC article.
A Novel AAV-mediated Gene Delivery System Corrects CFTR Function in Pigs.
Cooney AL, Thornell IM, Singh BK, Shah VS, Stoltz DA, McCray PB Jr, Zabner J, Sinn PL. Cooney AL, et al. Among authors: shah vs. Am J Respir Cell Mol Biol. 2019 Dec;61(6):747-754. doi: 10.1165/rcmb.2019-0006OC. Am J Respir Cell Mol Biol. 2019. PMID: 31184507 Free PMC article.
117 results