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Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes.
Wood AR, Tuke MA, Nalls M, Hernandez D, Gibbs JR, Lin H, Xu CS, Li Q, Shen J, Jun G, Almeida M, Tanaka T, Perry JR, Gaulton K, Rivas M, Pearson R, Curran JE, Johnson MP, Göring HH, Duggirala R, Blangero J, Mccarthy MI, Bandinelli S, Murray A, Weedon MN, Singleton A, Melzer D, Ferrucci L, Frayling TM. Wood AR, et al. Among authors: almeida m. Hum Mol Genet. 2015 Mar 1;24(5):1504-12. doi: 10.1093/hmg/ddu560. Epub 2014 Nov 6. Hum Mol Genet. 2015. PMID: 25378555 Free PMC article.
Plasma lipidome is independently associated with variability in metabolic syndrome in Mexican American families.
Kulkarni H, Meikle PJ, Mamtani M, Weir JM, Almeida M, Diego V, Peralta JM, Barlow CK, Bellis C, Dyer TD, Almasy L, Mahaney MC, Comuzzie AG, Göring HH, Curran JE, Blangero J. Kulkarni H, et al. Among authors: almeida m. J Lipid Res. 2014 May;55(5):939-46. doi: 10.1194/jlr.M044065. Epub 2014 Mar 13. J Lipid Res. 2014. PMID: 24627127 Free PMC article.
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes.
Majithia AR, Flannick J, Shahinian P, Guo M, Bray MA, Fontanillas P, Gabriel SB; GoT2D Consortium; NHGRI JHS/FHS Allelic Spectrum Project; SIGMA T2D Consortium; T2D-GENES Consortium; Rosen ED, Altshuler D. Majithia AR, et al. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13127-32. doi: 10.1073/pnas.1410428111. Epub 2014 Aug 25. Proc Natl Acad Sci U S A. 2014. PMID: 25157153 Free PMC article.
Human plasma lipidome is pleiotropically associated with cardiovascular risk factors and death.
Bellis C, Kulkarni H, Mamtani M, Kent JW Jr, Wong G, Weir JM, Barlow CK, Diego V, Almeida M, Dyer TD, Göring HHH, Almasy L, Mahaney MC, Comuzzie AG, Williams-Blangero S, Meikle PJ, Blangero J, Curran JE. Bellis C, et al. Among authors: almeida m. Circ Cardiovasc Genet. 2014 Dec;7(6):854-863. doi: 10.1161/CIRCGENETICS.114.000600. Epub 2014 Nov 2. Circ Cardiovasc Genet. 2014. PMID: 25363705 Free PMC article.
Data for Genetic Analysis Workshop 18: human whole genome sequence, blood pressure, and simulated phenotypes in extended pedigrees.
Almasy L, Dyer TD, Peralta JM, Jun G, Wood AR, Fuchsberger C, Almeida MA, Kent JW Jr, Fowler S, Blackwell TW, Puppala S, Kumar S, Curran JE, Lehman D, Abecasis G, Duggirala R, Blangero J; T2D-GENES Consortium. Almasy L, et al. Among authors: almeida ma. BMC Proc. 2014 Jun 17;8(Suppl 1):S2. doi: 10.1186/1753-6561-8-S1-S2. eCollection 2014. BMC Proc. 2014. PMID: 25519314 Free PMC article.
Pedigree-based random effect tests to screen gene pathways.
Almeida M, Peralta JM, Farook V, Puppala S, Kent JW Jr, Duggirala R, Blangero J. Almeida M, et al. BMC Proc. 2014 Jun 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S100. doi: 10.1186/1753-6561-8-S1-S100. eCollection 2014. BMC Proc. 2014. PMID: 25519354 Free PMC article.
A variance component-based gene burden test.
Peralta JM, Almeida M, Kent JW Jr, Blangero J. Peralta JM, et al. Among authors: almeida m. BMC Proc. 2014 Jun 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S49. doi: 10.1186/1753-6561-8-S1-S49. eCollection 2014. BMC Proc. 2014. PMID: 25519388 Free PMC article.
Evaluation of estimated genetic values and their application to genome-wide investigation of systolic blood pressure.
Quillen EE, Voruganti VS, Chittoor G, Rubicz R, Peralta JM, Almeida MA, Kent JW Jr, Diego VP, Dyer TD, Comuzzie AG, Göring HH, Duggirala R, Almasy L, Blangero J. Quillen EE, et al. Among authors: almeida ma. BMC Proc. 2014 Jun 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S66. doi: 10.1186/1753-6561-8-S1-S66. eCollection 2014. BMC Proc. 2014. PMID: 25519398 Free PMC article.
Effects of copy number variable regions on local gene expression in white blood cells of Mexican Americans.
Blackburn A, Almeida M, Dean A, Curran JE, Johnson MP, Moses EK, Abraham LJ, Carless MA, Dyer TD, Kumar S, Almasy L, Mahaney MC, Comuzzie A, Williams-Blangero S, Blangero J, Lehman DM, Göring HH. Blackburn A, et al. Among authors: almeida m. Eur J Hum Genet. 2015 Sep;23(9):1229-35. doi: 10.1038/ejhg.2014.280. Epub 2015 Jan 14. Eur J Hum Genet. 2015. PMID: 25585699 Free PMC article.
4,349 results