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34 results

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A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory.
Swadling L, Capone S, Antrobus RD, Brown A, Richardson R, Newell EW, Halliday J, Kelly C, Bowen D, Fergusson J, Kurioka A, Ammendola V, Del Sorbo M, Grazioli F, Esposito ML, Siani L, Traboni C, Hill A, Colloca S, Davis M, Nicosia A, Cortese R, Folgori A, Klenerman P, Barnes E. Swadling L, et al. Among authors: esposito ml. Sci Transl Med. 2014 Nov 5;6(261):261ra153. doi: 10.1126/scitranslmed.3009185. Sci Transl Med. 2014. PMID: 25378645 Free PMC article. Clinical Trial.
Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man.
Barnes E, Folgori A, Capone S, Swadling L, Aston S, Kurioka A, Meyer J, Huddart R, Smith K, Townsend R, Brown A, Antrobus R, Ammendola V, Naddeo M, O'Hara G, Willberg C, Harrison A, Grazioli F, Esposito ML, Siani L, Traboni C, Oo Y, Adams D, Hill A, Colloca S, Nicosia A, Cortese R, Klenerman P. Barnes E, et al. Among authors: esposito ml. Sci Transl Med. 2012 Jan 4;4(115):115ra1. doi: 10.1126/scitranslmed.3003155. Sci Transl Med. 2012. PMID: 22218690 Free PMC article.
Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species.
Colloca S, Barnes E, Folgori A, Ammendola V, Capone S, Cirillo A, Siani L, Naddeo M, Grazioli F, Esposito ML, Ambrosio M, Sparacino A, Bartiromo M, Meola A, Smith K, Kurioka A, O'Hara GA, Ewer KJ, Anagnostou N, Bliss C, Hill AV, Traboni C, Klenerman P, Cortese R, Nicosia A. Colloca S, et al. Among authors: esposito ml. Sci Transl Med. 2012 Jan 4;4(115):115ra2. doi: 10.1126/scitranslmed.3002925. Sci Transl Med. 2012. PMID: 22218691 Free PMC article.
Role of IL28B gene polymorphism and cell-mediated immunity in spontaneous resolution of acute hepatitis C.
Spada E, Amoroso P, Taliani G, Zuccaro O, Chiriacò P, Maio P, Maio G, Esposito ML, Mariano C, Rinaldi R, Bellissima P, Tosti ME, Del Porto P, Francavilla R, Mellace V, Garbuglia AR, Folgori A, Mele A; Acute Hepatitis Italian Study Group. Spada E, et al. Among authors: esposito ml. Clin Infect Dis. 2013 Sep;57(6):803-11. doi: 10.1093/cid/cit402. Epub 2013 Jun 19. Clin Infect Dis. 2013. PMID: 23784926 Free PMC article.
Fusion of HCV nonstructural antigen to MHC class II-associated invariant chain enhances T-cell responses induced by vectored vaccines in nonhuman primates.
Capone S, Naddeo M, D'Alise AM, Abbate A, Grazioli F, Del Gaudio A, Del Sorbo M, Esposito ML, Ammendola V, Perretta G, Taglioni A, Colloca S, Nicosia A, Cortese R, Folgori A. Capone S, et al. Among authors: esposito ml. Mol Ther. 2014 May;22(5):1039-47. doi: 10.1038/mt.2014.15. Epub 2014 Jan 30. Mol Ther. 2014. PMID: 24476798 Free PMC article.
Mucosal delivery of a vectored RSV vaccine is safe and elicits protective immunity in rodents and nonhuman primates.
Pierantoni A, Esposito ML, Ammendola V, Napolitano F, Grazioli F, Abbate A, Del Sorbo M, Siani L, D'Alise AM, Taglioni A, Perretta G, Siccardi A, Soprana E, Panigada M, Thom M, Scarselli E, Folgori A, Colloca S, Taylor G, Cortese R, Nicosia A, Capone S, Vitelli A. Pierantoni A, et al. Among authors: esposito ml. Mol Ther Methods Clin Dev. 2015 May 20;2:15018. doi: 10.1038/mtm.2015.18. eCollection 2015. Mol Ther Methods Clin Dev. 2015. PMID: 26015988 Free PMC article.
Chronic hepatitis C viral infection subverts vaccine-induced T-cell immunity in humans.
Kelly C, Swadling L, Capone S, Brown A, Richardson R, Halliday J, von Delft A, Oo Y, Mutimer D, Kurioka A, Hartnell F, Collier J, Ammendola V, Del Sorbo M, Grazioli F, Esposito ML, Di Marco S, Siani L, Traboni C, Hill AV, Colloca S, Nicosia A, Cortese R, Folgori A, Klenerman P, Barnes E. Kelly C, et al. Among authors: esposito ml. Hepatology. 2016 May;63(5):1455-70. doi: 10.1002/hep.28294. Epub 2016 Jan 22. Hepatology. 2016. PMID: 26474390 Free PMC article.
Rapid Affinity Maturation of Novel Anti-PD-L1 Antibodies by a Fast Drop of the Antigen Concentration and FACS Selection of Yeast Libraries.
Cembrola B, Ruzza V, Troise F, Esposito ML, Sasso E, Cafaro V, Passariello M, Visconte F, Raia M, Del Vecchio L, D'Alise AM, Cortese R, Scarselli E, Zambrano N, De Lorenzo C, Nicosia A. Cembrola B, et al. Among authors: esposito ml. Biomed Res Int. 2019 Dec 28;2019:6051870. doi: 10.1155/2019/6051870. eCollection 2019. Biomed Res Int. 2019. PMID: 31976323 Free PMC article.
MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans.
Esposito I, Cicconi P, D'Alise AM, Brown A, Esposito M, Swadling L, Holst PJ, Bassi MR, Stornaiuolo M, Mori F, Vassilev V, Li W, Donnison T, Gentile C, Turner B, von Delft A, Del Sorbo M, Barra F, Contino AM, Abbate A, Novellino E, Thomsen AR, Christensen JP, Lahm A, Grazioli F, Ammendola V, Siani L, Colloca S, Klenerman P, Nicosia A, Dorrell L, Folgori A, Capone S, Barnes E; PEACHI Consortium. Esposito I, et al. Sci Transl Med. 2020 Jun 17;12(548):eaaz7715. doi: 10.1126/scitranslmed.aaz7715. Sci Transl Med. 2020. PMID: 32554708 Free PMC article.
34 results