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A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory.
Swadling L, Capone S, Antrobus RD, Brown A, Richardson R, Newell EW, Halliday J, Kelly C, Bowen D, Fergusson J, Kurioka A, Ammendola V, Del Sorbo M, Grazioli F, Esposito ML, Siani L, Traboni C, Hill A, Colloca S, Davis M, Nicosia A, Cortese R, Folgori A, Klenerman P, Barnes E. Swadling L, et al. Among authors: fergusson j. Sci Transl Med. 2014 Nov 5;6(261):261ra153. doi: 10.1126/scitranslmed.3009185. Sci Transl Med. 2014. PMID: 25378645 Free PMC article. Clinical Trial.
CD161(int)CD8+ T cells: a novel population of highly functional, memory CD8+ T cells enriched within the gut.
Fergusson JR, Hühn MH, Swadling L, Walker LJ, Kurioka A, Llibre A, Bertoletti A, Holländer G, Newell EW, Davis MM, Sverremark-Ekström E, Powrie F, Capone S, Folgori A, Barnes E, Willberg CB, Ussher JE, Klenerman P. Fergusson JR, et al. Mucosal Immunol. 2016 Mar;9(2):401-13. doi: 10.1038/mi.2015.69. Epub 2015 Jul 29. Mucosal Immunol. 2016. PMID: 26220166 Free PMC article.
CD161 defines a transcriptional and functional phenotype across distinct human T cell lineages.
Fergusson JR, Smith KE, Fleming VM, Rajoriya N, Newell EW, Simmons R, Marchi E, Björkander S, Kang YH, Swadling L, Kurioka A, Sahgal N, Lockstone H, Baban D, Freeman GJ, Sverremark-Ekström E, Davis MM, Davenport MP, Venturi V, Ussher JE, Willberg CB, Klenerman P. Fergusson JR, et al. Cell Rep. 2014 Nov 6;9(3):1075-88. doi: 10.1016/j.celrep.2014.09.045. Epub 2014 Oct 23. Cell Rep. 2014. PMID: 25437561 Free PMC article.
CD161-expressing human T cells.
Fergusson JR, Fleming VM, Klenerman P. Fergusson JR, et al. Front Immunol. 2011 Aug 30;2:36. doi: 10.3389/fimmu.2011.00036. eCollection 2011. Front Immunol. 2011. PMID: 22566826 Free PMC article.
Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency.
Simoni Y, Fehlings M, Kløverpris HN, McGovern N, Koo SL, Loh CY, Lim S, Kurioka A, Fergusson JR, Tang CL, Kam MH, Dennis K, Lim TKH, Fui ACY, Hoong CW, Chan JKY, Curotto de Lafaille M, Narayanan S, Baig S, Shabeer M, Toh SES, Tan HKK, Anicete R, Tan EH, Takano A, Klenerman P, Leslie A, Tan DSW, Tan IB, Ginhoux F, Newell EW. Simoni Y, et al. Immunity. 2017 Jan 17;46(1):148-161. doi: 10.1016/j.immuni.2016.11.005. Epub 2016 Dec 13. Immunity. 2017. PMID: 27986455 Free PMC article.
Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection.
Cosgrove C, Ussher JE, Rauch A, Gärtner K, Kurioka A, Hühn MH, Adelmann K, Kang YH, Fergusson JR, Simmonds P, Goulder P, Hansen TH, Fox J, Günthard HF, Khanna N, Powrie F, Steel A, Gazzard B, Phillips RE, Frater J, Uhlig H, Klenerman P. Cosgrove C, et al. Among authors: fergusson jr. Blood. 2013 Feb 7;121(6):951-61. doi: 10.1182/blood-2012-06-436436. Epub 2012 Dec 18. Blood. 2013. PMID: 23255555 Free PMC article.
Shared and Distinct Phenotypes and Functions of Human CD161++ Vα7.2+ T Cell Subsets.
Kurioka A, Jahun AS, Hannaway RF, Walker LJ, Fergusson JR, Sverremark-Ekström E, Corbett AJ, Ussher JE, Willberg CB, Klenerman P. Kurioka A, et al. Among authors: fergusson jr. Front Immunol. 2017 Aug 30;8:1031. doi: 10.3389/fimmu.2017.01031. eCollection 2017. Front Immunol. 2017. PMID: 28912775 Free PMC article.
165 results