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528 results

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Page 1
Molecular Mechanism for Hypertensive Renal Disease: Differential Regulation of Chromogranin A Expression at 3'-Untranslated Region Polymorphism C+87T by MicroRNA-107.
Zhang K, Mir SA, Hightower CM, Miramontes-Gonzalez JP, Maihofer AX, Chen Y, Mahata SK, Nievergelt CM, Schork NJ, Freedman BI, Vaingankar SM, O'Connor DT. Zhang K, et al. Among authors: schork nj. J Am Soc Nephrol. 2015 Aug;26(8):1816-25. doi: 10.1681/ASN.2014060537. Epub 2014 Nov 12. J Am Soc Nephrol. 2015. PMID: 25392232 Free PMC article.
Chromogranin A polymorphisms are associated with hypertensive renal disease.
Salem RM, Cadman PE, Chen Y, Rao F, Wen G, Hamilton BA, Rana BK, Smith DW, Stridsberg M, Ward HJ, Mahata M, Mahata SK, Bowden DW, Hicks PJ, Freedman BI, Schork NJ, O'Connor DT. Salem RM, et al. Among authors: schork nj. J Am Soc Nephrol. 2008 Mar;19(3):600-14. doi: 10.1681/ASN.2007070754. Epub 2008 Jan 30. J Am Soc Nephrol. 2008. PMID: 18235090 Free PMC article.
Naturally occurring human genetic variation in the 3'-untranslated region of the secretory protein chromogranin A is associated with autonomic blood pressure regulation and hypertension in a sex-dependent fashion.
Chen Y, Rao F, Rodriguez-Flores JL, Mahata M, Fung MM, Stridsberg M, Vaingankar SM, Wen G, Salem RM, Das M, Cockburn MG, Schork NJ, Ziegler MG, Hamilton BA, Mahata SK, Taupenot L, O'Connor DT. Chen Y, et al. Among authors: schork nj. J Am Coll Cardiol. 2008 Oct 28;52(18):1468-81. doi: 10.1016/j.jacc.2008.07.047. J Am Coll Cardiol. 2008. PMID: 19017515 Free PMC article.
MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension.
Friese RS, Altshuler AE, Zhang K, Miramontes-Gonzalez JP, Hightower CM, Jirout ML, Salem RM, Gayen JR, Mahapatra NR, Biswas N, Cale M, Vaingankar SM, Kim HS, Courel M, Taupenot L, Ziegler MG, Schork NJ, Pravenec M, Mahata SK, Schmid-Schönbein GW, O'Connor DT. Friese RS, et al. Among authors: schork nj. Hum Mol Genet. 2013 Sep 15;22(18):3624-40. doi: 10.1093/hmg/ddt213. Epub 2013 May 13. Hum Mol Genet. 2013. PMID: 23674521 Free PMC article.
Heredity of endothelin secretion: human twin studies reveal the influence of polymorphism at the chromogranin A locus, a novel determinant of endothelial function.
Lillie EO, Mahata M, Khandrika S, Rao F, Bundey RA, Wen G, Chen Y, Taupenot L, Smith DW, Mahata SK, Ziegler MG, Cockburn M, Schork NJ, O'Connor DT. Lillie EO, et al. Among authors: schork nj. Circulation. 2007 May 1;115(17):2282-91. doi: 10.1161/CIRCULATIONAHA.106.648345. Epub 2007 Apr 16. Circulation. 2007. PMID: 17438153
Catecholamine release-inhibitory peptide catestatin (chromogranin A(352-372)): naturally occurring amino acid variant Gly364Ser causes profound changes in human autonomic activity and alters risk for hypertension.
Rao F, Wen G, Gayen JR, Das M, Vaingankar SM, Rana BK, Mahata M, Kennedy BP, Salem RM, Stridsberg M, Abel K, Smith DW, Eskin E, Schork NJ, Hamilton BA, Ziegler MG, Mahata SK, O'Connor DT. Rao F, et al. Among authors: schork nj. Circulation. 2007 May 1;115(17):2271-81. doi: 10.1161/CIRCULATIONAHA.106.628859. Epub 2007 Apr 16. Circulation. 2007. PMID: 17438154
Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk.
Zhang L, Rao F, Zhang K, Khandrika S, Das M, Vaingankar SM, Bao X, Rana BK, Smith DW, Wessel J, Salem RM, Rodriguez-Flores JL, Mahata SK, Schork NJ, Ziegler MG, O'Connor DT. Zhang L, et al. Among authors: schork nj. J Clin Invest. 2007 Sep;117(9):2658-71. doi: 10.1172/JCI31093. J Clin Invest. 2007. PMID: 17717598 Free PMC article.
Biogenesis of the secretory granule: chromogranin A coiled-coil structure results in unusual physical properties and suggests a mechanism for granule core condensation.
Mosley CA, Taupenot L, Biswas N, Taulane JP, Olson NH, Vaingankar SM, Wen G, Schork NJ, Ziegler MG, Mahata SK, O'Connor DT. Mosley CA, et al. Among authors: schork nj. Biochemistry. 2007 Sep 25;46(38):10999-1012. doi: 10.1021/bi700704r. Epub 2007 Aug 24. Biochemistry. 2007. PMID: 17718510
528 results