Ou SH - Search Results

1

Identification of a novel HIP1-ALK fusion variant in Non-Small-Cell Lung Cancer (NSCLC) and discovery of ALK I1171 (I1171N/S) mutations in two ALK-rearranged NSCLC patients with resistance to Alectinib.

Ou SH, Klempner SJ, Greenbowe JR, Azada M, Schrock AB, Ali SM, Ross JS, Stephens PJ, Miller VA. Ou SH, et al. J Thorac Oncol. 2014 Dec;9(12):1821-5. doi: 10.1097/JTO.0000000000000368. J Thorac Oncol. 2014. PMID: 25393796 Free article.

2

Asymptomatic profound sinus bradycardia (heart rate ≤45) in non-small cell lung cancer patients treated with crizotinib.

Ou SH, Azada M, Dy J, Stiber JA. Ou SH, et al. J Thorac Oncol. 2011 Dec;6(12):2135-7. doi: 10.1097/JTO.0b013e3182307e06. J Thorac Oncol. 2011. PMID: 22088989 Free article. Clinical Trial.

3

Heart rate decrease during crizotinib treatment and potential correlation to clinical response.

Ou SH, Tong WP, Azada M, Siwak-Tapp C, Dy J, Stiber JA. Ou SH, et al. Cancer. 2013 Jun 1;119(11):1969-75. doi: 10.1002/cncr.28040. Epub 2013 Mar 15. Cancer. 2013. PMID: 23505007 Free article. Clinical Trial.

4

Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG): results from the dose-finding portion of a phase 1/2 study.

Gadgeel SM, Gandhi L, Riely GJ, Chiappori AA, West HL, Azada MC, Morcos PN, Lee RM, Garcia L, Yu L, Boisserie F, Di Laurenzio L, Golding S, Sato J, Yokoyama S, Tanaka T, Ou SH. Gadgeel SM, et al. Among authors: ou sh. Lancet Oncol. 2014 Sep;15(10):1119-28. doi: 10.1016/S1470-2045(14)70362-6. Epub 2014 Aug 18. Lancet Oncol. 2014. PMID: 25153538 Clinical Trial.

5

Choroidal metastasis response to crizotinib in a ROS1-rearranged NSCLC patient.

Lu S, Azada MC, Ou SH. Lu S, et al. Among authors: ou sh. Lung Cancer. 2015 Feb;87(2):207-9. doi: 10.1016/j.lungcan.2014.12.011. Epub 2014 Dec 19. Lung Cancer. 2015. PMID: 25558789

6

Alectinib induces a durable (>15 months) complete response in an ALK-positive non-small cell lung cancer patient who progressed on crizotinib with diffuse leptomeningeal carcinomatosis.

Ou SH, Sommers KR, Azada MC, Garon EB. Ou SH, et al. Oncologist. 2015 Feb;20(2):224-6. doi: 10.1634/theoncologist.2014-0309. Epub 2015 Jan 7. Oncologist. 2015. PMID: 25568147 Free PMC article.

7

I1171 missense mutation (particularly I1171N) is a common resistance mutation in ALK-positive NSCLC patients who have progressive disease while on alectinib and is sensitive to ceritinib.

Ou SH, Greenbowe J, Khan ZU, Azada MC, Ross JS, Stevens PJ, Ali SM, Miller VA, Gitlitz B. Ou SH, et al. Lung Cancer. 2015 May;88(2):231-4. doi: 10.1016/j.lungcan.2015.02.005. Epub 2015 Feb 12. Lung Cancer. 2015. PMID: 25736571

8

Identification of a novel TMEM106B-ROS1 fusion variant in lung adenocarcinoma by comprehensive genomic profiling.

Ou SH, Chalmers ZR, Azada MC, Ross JS, Stephens PJ, Ali SM, Miller VA. Ou SH, et al. Lung Cancer. 2015 Jun;88(3):352-4. doi: 10.1016/j.lungcan.2015.03.014. Epub 2015 Mar 21. Lung Cancer. 2015. PMID: 25851827

9

Radiation necrosis presenting as pseudoprogression (PsP) during alectinib treatment of previously radiated brain metastases in ALK-positive NSCLC: Implications for disease assessment and management.

Ou SH, Klempner SJ, Azada MC, Rausei-Mills V, Duma C. Ou SH, et al. Lung Cancer. 2015 Jun;88(3):355-9. doi: 10.1016/j.lungcan.2015.03.022. Epub 2015 Mar 30. Lung Cancer. 2015. PMID: 25882777

10

The Clinical Use of Genomic Profiling to Distinguish Intrapulmonary Metastases From Synchronous Primaries in Non-Small-Cell Lung Cancer: A Mini-Review.

Klempner SJ, Ou SH, Costa DB, VanderLaan PA, Sanford EM, Schrock A, Gay L, Ali SM, Miller VA. Klempner SJ, et al. Among authors: ou sh. Clin Lung Cancer. 2015 Sep;16(5):334-339.e1. doi: 10.1016/j.cllc.2015.03.004. Epub 2015 Mar 26. Clin Lung Cancer. 2015. PMID: 25911330 Review.

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