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Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid-derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model.
Yan J, Tingey C, Lyde R, Gorham TC, Choo DK, Muthumani A, Myles D, Weiner LP, Kraynyak KA, Reuschel EL, Finkel TH, Kim JJ, Sardesai NY, Ugen KE, Muthumani K, Weiner DB. Yan J, et al. Cancer Gene Ther. 2014 Dec;21(12):507-17. doi: 10.1038/cgt.2014.56. Epub 2014 Nov 14. Cancer Gene Ther. 2014. PMID: 25394503
Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity.
Shedlock DJ, Tingey C, Mahadevan L, Hutnick N, Reuschel EL, Kudchodkar S, Flingai S, Yan J, Kim JJ, Ugen KE, Weiner DB, Muthumani K. Shedlock DJ, et al. Among authors: yan j. Vaccines (Basel). 2014 Mar 25;2(2):196-215. doi: 10.3390/vaccines2020196. Vaccines (Basel). 2014. PMID: 26344618 Free PMC article.
Inducing humoral and cellular responses to multiple sporozoite and liver-stage malaria antigens using exogenous plasmid DNA.
Ferraro B, Talbott KT, Balakrishnan A, Cisper N, Morrow MP, Hutnick NA, Myles DJ, Shedlock DJ, Obeng-Adjei N, Yan J, Kayatani AK, Richie N, Cabrera W, Shiver R, Khan AS, Brown AS, Yang M, Wille-Reece U, Birkett AJ, Sardesai NY, Weiner DB. Ferraro B, et al. Among authors: yan j. Infect Immun. 2013 Oct;81(10):3709-20. doi: 10.1128/IAI.00180-13. Epub 2013 Jul 29. Infect Immun. 2013. PMID: 23897618 Free PMC article.
CCR10 expression is required for the adjuvant activity of the mucosal chemokine CCL28 when delivered in the context of an HIV-1 Env DNA vaccine.
Gary EN, Kathuria N, Makurumidze G, Curatola A, Ramamurthi A, Bernui ME, Myles D, Yan J, Pankhong P, Muthumani K, Haddad E, Humeau L, Weiner DB, Kutzler MA. Gary EN, et al. Among authors: yan j. Vaccine. 2020 Mar 4;38(11):2626-2635. doi: 10.1016/j.vaccine.2020.01.023. Epub 2020 Feb 10. Vaccine. 2020. PMID: 32057572 Free PMC article.
Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge.
Kutzler MA, Wise MC, Hutnick NA, Moldoveanu Z, Hunter M, Reuter M, Yuan S, Yan J, Ginsberg A, Sylvester A, Pahar B, Carnathan D, Kathuria N, Khan AS, Montefiori D, Sardesai NY, Betts MR, Mestecky J, Marx P, Weiner DB. Kutzler MA, et al. Among authors: yan j. Mucosal Immunol. 2016 Jan;9(1):13-23. doi: 10.1038/mi.2015.31. Epub 2015 May 6. Mucosal Immunol. 2016. PMID: 25943275 Free PMC article.
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