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Page 1
Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease.
Francelle L, Galvan L, Gaillard MC, Guillermier M, Houitte D, Bonvento G, Petit F, Jan C, Dufour N, Hantraye P, Elalouf JM, De Chaldée M, Déglon N, Brouillet E. Francelle L, et al. Among authors: hantraye p. Hum Mol Genet. 2015 Mar 15;24(6):1563-73. doi: 10.1093/hmg/ddu571. Epub 2014 Nov 14. Hum Mol Genet. 2015. PMID: 25398949 Free PMC article.
Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II.
Benchoua A, Trioulier Y, Diguet E, Malgorn C, Gaillard MC, Dufour N, Elalouf JM, Krajewski S, Hantraye P, Déglon N, Brouillet E. Benchoua A, et al. Among authors: hantraye p. Hum Mol Genet. 2008 May 15;17(10):1446-56. doi: 10.1093/hmg/ddn033. Epub 2008 Feb 11. Hum Mol Genet. 2008. PMID: 18267960 Free PMC article.
In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects.
Faideau M, Kim J, Cormier K, Gilmore R, Welch M, Auregan G, Dufour N, Guillermier M, Brouillet E, Hantraye P, Déglon N, Ferrante RJ, Bonvento G. Faideau M, et al. Among authors: hantraye p. Hum Mol Genet. 2010 Aug 1;19(15):3053-67. doi: 10.1093/hmg/ddq212. Epub 2010 May 21. Hum Mol Genet. 2010. PMID: 20494921 Free PMC article.
A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin.
Damiano M, Diguet E, Malgorn C, D'Aurelio M, Galvan L, Petit F, Benhaim L, Guillermier M, Houitte D, Dufour N, Hantraye P, Canals JM, Alberch J, Delzescaux T, Déglon N, Beal MF, Brouillet E. Damiano M, et al. Among authors: hantraye p. Hum Mol Genet. 2013 Oct 1;22(19):3869-82. doi: 10.1093/hmg/ddt242. Epub 2013 May 29. Hum Mol Genet. 2013. PMID: 23720495 Free PMC article.
Striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo.
Francelle L, Galvan L, Gaillard MC, Petit F, Bernay B, Guillermier M, Bonvento G, Dufour N, Elalouf JM, Hantraye P, Déglon N, de Chaldée M, Brouillet E. Francelle L, et al. Among authors: hantraye p. Neurobiol Aging. 2015 Mar;36(3):1601.e7-16. doi: 10.1016/j.neurobiolaging.2014.11.014. Epub 2014 Dec 18. Neurobiol Aging. 2015. PMID: 25619660 Free article.
The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin.
Galvan L, Francelle L, Gaillard MC, de Longprez L, Carrillo-de Sauvage MA, Liot G, Cambon K, Stimmer L, Luccantoni S, Flament J, Valette J, de Chaldée M, Auregan G, Guillermier M, Joséphine C, Petit F, Jan C, Jarrige M, Dufour N, Bonvento G, Humbert S, Saudou F, Hantraye P, Merienne K, Bemelmans AP, Perrier AL, Déglon N, Brouillet E. Galvan L, et al. Among authors: hantraye p. Brain. 2018 May 1;141(5):1434-1454. doi: 10.1093/brain/awy057. Brain. 2018. PMID: 29534157 Free PMC article.
Engineered lentiviral vector targeting astrocytes in vivo.
Colin A, Faideau M, Dufour N, Auregan G, Hassig R, Andrieu T, Brouillet E, Hantraye P, Bonvento G, Déglon N. Colin A, et al. Among authors: hantraye p. Glia. 2009 Apr 15;57(6):667-79. doi: 10.1002/glia.20795. Glia. 2009. PMID: 18942755
243 results