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Conformation determines the seeding potencies of native and recombinant Tau aggregates.
Falcon B, Cavallini A, Angers R, Glover S, Murray TK, Barnham L, Jackson S, O'Neill MJ, Isaacs AM, Hutton ML, Szekeres PG, Goedert M, Bose S. Falcon B, et al. Among authors: barnham l. J Biol Chem. 2015 Jan 9;290(2):1049-65. doi: 10.1074/jbc.M114.589309. Epub 2014 Nov 18. J Biol Chem. 2015. PMID: 25406315 Free PMC article.
Development of a Scalable, High-Throughput-Compatible Assay to Detect Tau Aggregates Using iPSC-Derived Cortical Neurons Maintained in a Three-Dimensional Culture Format.
Medda X, Mertens L, Versweyveld S, Diels A, Barnham L, Bretteville A, Buist A, Verheyen A, Royaux I, Ebneth A, Cabrera-Socorro A. Medda X, et al. Among authors: barnham l. J Biomol Screen. 2016 Sep;21(8):804-15. doi: 10.1177/1087057116638029. Epub 2016 Mar 16. J Biomol Screen. 2016. PMID: 26984927