Pflug A - Search Results

1

Structural insight into cap-snatching and RNA synthesis by influenza polymerase.

Reich S, Guilligay D, Pflug A, Malet H, Berger I, Crépin T, Hart D, Lunardi T, Nanao M, Ruigrok RW, Cusack S. Reich S, et al. Among authors: pflug a. Nature. 2014 Dec 18;516(7531):361-6. doi: 10.1038/nature14009. Epub 2014 Nov 19. Nature. 2014. PMID: 25409151

2

Structure of influenza A polymerase bound to the viral RNA promoter.

Pflug A, Guilligay D, Reich S, Cusack S. Pflug A, et al. Nature. 2014 Dec 18;516(7531):355-60. doi: 10.1038/nature14008. Epub 2014 Nov 19. Nature. 2014. PMID: 25409142

3

Structural basis of an essential interaction between influenza polymerase and Pol II CTD.

Lukarska M, Fournier G, Pflug A, Resa-Infante P, Reich S, Naffakh N, Cusack S. Lukarska M, et al. Among authors: pflug a. Nature. 2017 Jan 5;541(7635):117-121. doi: 10.1038/nature20594. Epub 2016 Dec 21. Nature. 2017. PMID: 28002402

4

Structural insights into RNA synthesis by the influenza virus transcription-replication machine.

Pflug A, Lukarska M, Resa-Infante P, Reich S, Cusack S. Pflug A, et al. Virus Res. 2017 Apr 15;234:103-117. doi: 10.1016/j.virusres.2017.01.013. Epub 2017 Jan 20. Virus Res. 2017. PMID: 28115197 Free article. Review.

5

Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.

Pflug A, Gaudon S, Resa-Infante P, Lethier M, Reich S, Schulze WM, Cusack S. Pflug A, et al. Nucleic Acids Res. 2018 Jan 25;46(2):956-971. doi: 10.1093/nar/gkx1210. Nucleic Acids Res. 2018. PMID: 29202182 Free PMC article.

6

Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains.

Thierry E, Guilligay D, Kosinski J, Bock T, Gaudon S, Round A, Pflug A, Hengrung N, El Omari K, Baudin F, Hart DJ, Beck M, Cusack S. Thierry E, et al. Among authors: pflug a. Mol Cell. 2016 Jan 7;61(1):125-37. doi: 10.1016/j.molcel.2015.11.016. Epub 2015 Dec 17. Mol Cell. 2016. PMID: 26711008 Free PMC article.

7

A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.

Wandzik JM, Kouba T, Karuppasamy M, Pflug A, Drncova P, Provaznik J, Azevedo N, Cusack S. Wandzik JM, et al. Among authors: pflug a. Cell. 2020 May 14;181(4):877-893.e21. doi: 10.1016/j.cell.2020.03.061. Epub 2020 Apr 17. Cell. 2020. PMID: 32304664 Free article.

8

Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD.

Krischuns T, Isel C, Drncova P, Lukarska M, Pflug A, Paisant S, Navratil V, Cusack S, Naffakh N. Krischuns T, et al. Among authors: pflug a. PLoS Pathog. 2022 May 23;18(5):e1010328. doi: 10.1371/journal.ppat.1010328. eCollection 2022 May. PLoS Pathog. 2022. PMID: 35605026 Free PMC article.

9

Structural basis of eukaryotic cell targeting by type III secretion system (T3SS) effectors.

Tosi T, Pflug A, Discola KF, Neves D, Dessen A. Tosi T, et al. Among authors: pflug a. Res Microbiol. 2013 Jul-Aug;164(6):605-19. doi: 10.1016/j.resmic.2013.03.019. Epub 2013 Mar 26. Res Microbiol. 2013. PMID: 23541478 Free article. Review.

10

Anomalous dispersion analysis of inhibitor flexibility: a case study of the kinase inhibitor H-89.

Pflug A, Johnson KA, Engh RA. Pflug A, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Aug 1;68(Pt 8):873-7. doi: 10.1107/S1744309112028655. Epub 2012 Jul 26. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22869112 Free PMC article.

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