Wu TY - Search Results

1

Rational design of small molecules as vaccine adjuvants.

Wu TY, Singh M, Miller AT, De Gregorio E, Doro F, D'Oro U, Skibinski DA, Mbow ML, Bufali S, Herman AE, Cortez A, Li Y, Nayak BP, Tritto E, Filippi CM, Otten GR, Brito LA, Monaci E, Li C, Aprea S, Valentini S, Calabrό S, Laera D, Brunelli B, Caproni E, Malyala P, Panchal RG, Warren TK, Bavari S, O'Hagan DT, Cooke MP, Valiante NM. Wu TY, et al. Sci Transl Med. 2014 Nov 19;6(263):263ra160. doi: 10.1126/scitranslmed.3009980. Sci Transl Med. 2014. PMID: 25411473

2

A new TLR2 agonist promotes cross-presentation by mouse and human antigen presenting cells.

Santone M, Aprea S, Wu TY, Cooke MP, Mbow ML, Valiante NM, Rush JS, Dougan S, Avalos A, Ploegh H, De Gregorio E, Buonsanti C, D'Oro U. Santone M, et al. Among authors: wu ty. Hum Vaccin Immunother. 2015;11(8):2038-50. doi: 10.1080/21645515.2015.1027467. Hum Vaccin Immunother. 2015. PMID: 26024409 Free PMC article.

3

Incorporation of Phosphonate into Benzonaphthyridine Toll-like Receptor 7 Agonists for Adsorption to Aluminum Hydroxide.

Cortez A, Li Y, Miller AT, Zhang X, Yue K, Maginnis J, Hampton J, Hall de S, Shapiro M, Nayak B, D'Oro U, Li C, Skibinski D, Mbow ML, Singh M, O'Hagan DT, Cooke MP, Valiante NM, Wu TY. Cortez A, et al. Among authors: wu ty. J Med Chem. 2016 Jun 23;59(12):5868-78. doi: 10.1021/acs.jmedchem.6b00489. Epub 2016 Jun 13. J Med Chem. 2016. PMID: 27270029

4

Stable Nanoemulsions for the Delivery of Small Molecule Immune Potentiators.

Lodaya RN, Brito LA, Wu TYH, Miller AT, Otten GR, Singh M, O'Hagan DT. Lodaya RN, et al. J Pharm Sci. 2018 Sep;107(9):2310-2314. doi: 10.1016/j.xphs.2018.05.012. Epub 2018 Jun 5. J Pharm Sci. 2018. PMID: 29883663

5

A Novel Toll-Like Receptor 2 Agonist Protects Mice in a Prophylactic Treatment Model Against Challenge With Bacillus anthracis.

Chiang CY, Lane DJ, Zou Y, Hoffman T, Pan J, Hampton J, Maginnis J, Nayak BP, D'Oro U, Valiante N, Miller AT, Cooke M, Wu T, Bavari S, Panchal RG. Chiang CY, et al. Front Microbiol. 2022 Mar 14;13:803041. doi: 10.3389/fmicb.2022.803041. eCollection 2022. Front Microbiol. 2022. PMID: 35369443 Free PMC article.

6

Topical SMIP-7.7, a toll-like receptor 7 agonist, protects against genital herpes simplex virus type-2 disease in the guinea pig model of genital herpes.

Bernstein DI, Cardin RD, Bravo FJ, Earwood J, Clark JR, Li Y, Mishra P, Li C, Nayak BP, Miller AT, Wu TY, Cooke MP, Valiante NM. Bernstein DI, et al. Among authors: wu ty. Antivir Chem Chemother. 2014 Apr 11;23(5):189-96. doi: 10.3851/IMP2499. Antivir Chem Chemother. 2014. PMID: 23232327 Free article.

7

Pancreas-Specific Delivery of β-Cell Proliferating Small Molecules.

Hao X, Jin Q, Va P, Li C, Shen W, Laffitte B, Wu TY. Hao X, et al. Among authors: wu ty. ChemMedChem. 2016 Jun 6;11(11):1129-32. doi: 10.1002/cmdc.201600116. Epub 2016 Apr 20. ChemMedChem. 2016. PMID: 27095073

8

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.

Shen W, Taylor B, Jin Q, Nguyen-Tran V, Meeusen S, Zhang YQ, Kamireddy A, Swafford A, Powers AF, Walker J, Lamb J, Bursalaya B, DiDonato M, Harb G, Qiu M, Filippi CM, Deaton L, Turk CN, Suarez-Pinzon WL, Liu Y, Hao X, Mo T, Yan S, Li J, Herman AE, Hering BJ, Wu T, Martin Seidel H, McNamara P, Glynne R, Laffitte B. Shen W, et al. Nat Commun. 2015 Oct 26;6:8372. doi: 10.1038/ncomms9372. Nat Commun. 2015. PMID: 26496802 Free PMC article.

9

Liver-Targeted Toll-Like Receptor 7 Agonist Combined With Entecavir Promotes a Functional Cure in the Woodchuck Model of Hepatitis B Virus.

Korolowizc KE, Li B, Huang X, Yon C, Rodrigo E, Corpuz M, Plouffe DM, Kallakury BV, Suresh M, Wu TY, Miller AT, Menne S. Korolowizc KE, et al. Among authors: wu ty. Hepatol Commun. 2019 Jul 8;3(10):1296-1310. doi: 10.1002/hep4.1397. eCollection 2019 Oct. Hepatol Commun. 2019. PMID: 31592075 Free PMC article.

10

Small-molecule inducer of β cell proliferation identified by high-throughput screening.

Shen W, Tremblay MS, Deshmukh VA, Wang W, Filippi CM, Harb G, Zhang YQ, Kamireddy A, Baaten JE, Jin Q, Wu T, Swoboda JG, Cho CY, Li J, Laffitte BA, McNamara P, Glynne R, Wu X, Herman AE, Schultz PG. Shen W, et al. J Am Chem Soc. 2013 Feb 6;135(5):1669-72. doi: 10.1021/ja309304m. Epub 2013 Jan 25. J Am Chem Soc. 2013. PMID: 23330637

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