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In type 2 diabetes mellitus glycated albumin alters macrophage gene expression impairing ABCA1-mediated cholesterol efflux.
Machado-Lima A, Iborra RT, Pinto RS, Castilho G, Sartori CH, Oliveira ER, Okuda LS, Nakandakare ER, Giannella-Neto D, Machado UF, Corrêa-Giannella ML, Traldi P, Porcu S, Roverso M, Lapolla A, Passarelli M. Machado-Lima A, et al. Among authors: castilho g. J Cell Physiol. 2015 Jun;230(6):1250-7. doi: 10.1002/jcp.24860. J Cell Physiol. 2015. PMID: 25413254
N-acetylcysteine prevents endoplasmic reticulum stress elicited in macrophages by serum albumin drawn from chronic kidney disease rats and selectively affects lipid transporters, ABCA-1 and ABCG-1.
Machado JT, Iborra RT, Fusco FB, Castilho G, Pinto RS, Machado-Lima A, Nakandakare ER, Seguro AC, Shimizu MH, Catanozi S, Passarelli M. Machado JT, et al. Among authors: castilho g. Atherosclerosis. 2014 Nov;237(1):343-52. doi: 10.1016/j.atherosclerosis.2014.09.020. Epub 2014 Sep 30. Atherosclerosis. 2014. PMID: 25305669
Glycated human serum albumin isolated from poorly controlled diabetic patients impairs cholesterol efflux from macrophages: an investigation by mass spectrometry.
Traldi P, Castilho G, Sartori CH, Machado-Lima A, Nakandakare ER, Corrêa-Giannella ML, Roverso M, Porcu S, Lapolla A, Passarelli M. Traldi P, et al. Among authors: castilho g. Eur J Mass Spectrom (Chichester). 2015;21(3):233-44. doi: 10.1255/ejms.1322. Eur J Mass Spectrom (Chichester). 2015. PMID: 26307703
The impact of dietary fatty acids on macrophage cholesterol homeostasis.
Afonso Mda S, Castilho G, Lavrador MS, Passarelli M, Nakandakare ER, Lottenberg SA, Lottenberg AM. Afonso Mda S, et al. Among authors: castilho g. J Nutr Biochem. 2014 Feb;25(2):95-103. doi: 10.1016/j.jnutbio.2013.10.001. Epub 2013 Oct 31. J Nutr Biochem. 2014. PMID: 24445035 Review.
Aerobic exercise training enhances the in vivo cholesterol trafficking from macrophages to the liver independently of changes in the expression of genes involved in lipid flux in macrophages and aorta.
Pinto PR, Rocco DD, Okuda LS, Machado-Lima A, Castilho G, da Silva KS, Gomes DJ, Pinto Rde S, Iborra RT, Ferreira Gda S, Nakandakare ER, Machado UF, Correa-Giannella ML, Catanozi S, Passarelli M. Pinto PR, et al. Among authors: castilho g. Lipids Health Dis. 2015 Sep 16;14:109. doi: 10.1186/s12944-015-0093-3. Lipids Health Dis. 2015. PMID: 26377330 Free PMC article.
Dietary interesterified fat enriched with palmitic acid induces atherosclerosis by impairing macrophage cholesterol efflux and eliciting inflammation.
Afonso MS, Lavrador MS, Koike MK, Cintra DE, Ferreira FD, Nunes VS, Castilho G, Gioielli LA, Paula Bombo R, Catanozi S, Caldini EG, Damaceno-Rodrigues NR, Passarelli M, Nakandakare ER, Lottenberg AM. Afonso MS, et al. Among authors: castilho g. J Nutr Biochem. 2016 Jun;32:91-100. doi: 10.1016/j.jnutbio.2016.01.005. Epub 2016 Mar 4. J Nutr Biochem. 2016. PMID: 27142741
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